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PeRkinElmeR:从表型到靶点的药物研发流程

传统基于靶点(taRget-based)的药物研发流程耗费大量的时间(历时10年以上)和财力(数十亿美元),这种流程的成功率相当低,只在极少数的研发案例中出现能通过整个流程最终上市成为治疗疾病的药物,究其原因是从体外到体内的过程违背了药物发挥作用的基本原则,即只有在生理环境下有效果才算真正的效果。 R>R> 近年来越来越多的药物研发转变为始于表型研究,继而转入靶点研究的新流程。这个流程的核心在于先确定候选药物能否引起细胞生理形态的改变,进而确认作用靶点,辅以正交实验的方法,通过大数据分析得到坚实可靠的结果。 在这次研讨会中,我们的专家将会在以下方面与您探讨: R>R> (1).非标记检测在不用类型细胞表型研究中的应用R> (2).细胞成像在表型研究中的应用R> (3).靶点研究的最新实验方法R> (4).通过正交方法获得坚实可靠的实验结果

2016-05-31 课时:64分钟

从实验到分析——深度解析基于二代测序的LncRNA研究及应用

非编码RNA起初被认为是基因组转录的“垃圾”,而近年来,多个高水平的杂志以封面形式报道长链非编码RNA(long non-coding RNA,LncRNA)的重要性,由此LncRNAs引起了人们广泛的关注,已成为各研究领域的一颗新星。 本次讲座主要将从以下几个方面展开:R/> ①LncRNA的方案设计及研究思路R/> ②LncRNA的实验及分析流程R/> ③LncRNA的案例解析R/> ④LncRNA+mRNA+miRNA联合分析方案解析R/> ⑤一类特殊的ncRNA——ciRculaR RNA R/>

2016-06-02 课时:35分钟

PeRkinElmeR Company OveRview

At PeRkinElmeR we'Re taking action to impRove the health and safety of people and the enviRonment. We'Re committed to tRansfoRming Risk into safety, mysteRy into knowledge and ideas into action foR healthieR today and even betteR tomoRRow. We aRe committed to deliveRing solutions that impRove ouR customeRs' outcomes, advance human and enviRonmental health technologies and, deliveR shaReholdeR value. EveRy day, we woRk togetheR to ensuRe the way we do business is as meaningful as the solutions we pRovide.

2016-06-02 课时:2分钟

IntRoducing the EnSight™ Multimode Plate ReadeR fRom PeRkinElmeR

PeRkinElmeR's EnSight Multimode Plate ReadeR is the fiRst benchtop system to offeR well-imaging alongside label-fRee and labeled detection technologies - foR a whole new peRspective on youR ReseaRch. FoR moRe infoRmation, please visit the EnSight website - http://bit.ly/T4IDPh

2016-06-02 课时:4分钟

PRe-Clinical In Vivo Imaging Solutions fRom PeRkinElmeR

PeRkinElmeR offeRs a compRehensive poRtfolio of pRe-clinical in vivo imaging systems and Reagents. Find out moRe at http://bit.ly/1mnyvwF. OuR pRe-clinical imaging instRuments include ouR highly published (oveR 4000 citations) IVIS Optical imaging systems, Quantum FX micRoCT which deliveRs high quality images at an x-Ray dose low enough foR longitudinal studies, and x-Ray systems. We also offeR a laRge poRtfolio of in vivo imaging Reagents foR most aReas of ReseaRch including canceR, infectious disease, stem cell, inflammation, toxicology/dRug safety and moRe.

2016-06-02 课时:4分钟

PKI MantRa IntRo 2015

The MantRa™ quantitative pathology woRkstation lets you visualize, quantify, and phenotype multiple types of immune cells simultaneously in intact FFPE tissue sections foR canceR immunology ReseaRch. MantRa allows you to maintain tissue moRphology to help betteR undeRstand the types and Roles of cells within the tumoR and tumoR micRoenviRonment. The system comes with poweRful inFoRm® Tissue FindeR™ advanced image analysis softwaRe that featuRes useR-tRainable algoRithms foR automatic Recognition of specific tissue and cell types, as well as peR-cell analysis of biomaRkeR expRession and phenotyping to diffeRentiate among cell types. Pathology Views™ cReates familiaR-looking bRightfield (H&E, DAB, hematoxylin) RendeRings fRom oRiginal multi-label fluoRescence images. PeRkinElmeR’s canceR immunology woRkflow has been validated using Opal™ Reagent kits. Opal methodology enables specific staining of multiple tissue biomaRkeRs Reaching up to 6-plex and beyond in a single tissue section. LeaRn moRe: http://www.peRkinelmeR.com/catalog/pR...

2016-06-02 课时:7分钟

IntRoducing the OpeRa Phenix™ High Content ScReening System

IntRoducing OpeRa Phenix™, a next-geneRation, confocal, high content scReening system designed foR high-thRoughput, phenotypic scReening and assays using complex disease models, such as pRimaRy cells and micRotissues. Find out moRe at http://bit.ly/1eZM4Ok.

2016-06-02 课时:4分钟

TogetheR we can help Revolutionizing Medicine

TogetheR we can help Revolutionizing Medicine

2016-06-02 课时:3分钟

People coming togetheR makeing a diffeRence

People coming togetheR makeing a diffeRence

2016-06-02 课时:3分钟

HER2基因与肿瘤 - 陈巍学基因(40)

HER2基因,是乳腺癌和胃癌靶向治疗中重要的生物标志物。本视频介绍了这个基因,以及针对HER2的靶向治疗药物,和针对HER2基因异常扩增的临床检测方法。

2016-06-14 课时:12分钟