银屑病的新突破：以IL-17 通路为靶点
银屑病是一种慢性炎症性皮肤病，由免疫系统引发，其发病人数约占总人口的2-3%。最近，对免疫过程的研究取得了新的进展，带来了一些令人激动的新药物靶点。本视频主要介绍了IL-17如何被开发成治疗银屑病的新疗法。
肿瘤免疫学与免疫治疗的新进展
This animation created by Nature Reviews Cancer and Nature Reviews Immunology illustrates how tumour cells are sensed and destroyed by cells of the immune system and how tumours can evolve to evade immune-mediated elimination. Scientists are developing new immunotherapies that help the immune system to ‘fight back’ — the animation explains how these exciting new drugs work.
卵巢癌：治疗新突破
卵巢癌是第七大最常见的癌症，也是最难治疗的癌症之一。正如动画显示，这在很大程度上是因为许多肿瘤的发展能抵抗一线治疗：以铂为基础的化疗。好消息是，实验疗法的发展可能提供一种更好的方法，来击败致死性肿瘤。
霍乱弧菌群体感应和新型抗生素 - Bonnie Bassler P2
本视频由科普中国和生物医学大讲堂出品
Bonnie Bassler (Princeton) Part 2: Vibrio Cholerae Quorum Sensing and Novel Antibiotics
Bacteria, primitive single-celled organisms, communicate with chemical languages that allow them to synchronize their behavior and thereby act as enormous multi-cellular organisms. This process is called quorum sensing and it enables bacteria to successfully infect and cause disease in plants, animals, and humans. Investigations of the molecular mechanisms underlying quorum sensing are leading to the development of novel strategies to interfere with quorum sensing. These strategies form the basis of new therapies to be used as antibiotics. See more at http://www.ibioseminars.org
多细胞生物的新研究 - Richard Losick P2
本视频由科普中国和生物医学大讲堂出品
Richard Losick (Harvard) Part 2: New Research on Multicellularity
Part II presents research on the capacity of B. subtilis cells to form architecturally complex communities.
用CRISPR寻找新肿瘤药 - 陈巍学基因（32）
欢迎来到【陈巍学基因】，我们这个节目，主要是给大家介绍基因组学，和临床分子诊断的最新技术进展。
今天要和大家谈的，是用CRISPR方法，来寻找新的、可能的肿瘤药物。
提出这个方法的，是加拿大Donnelly Centre的Traver Hart。Traver Hart把他的这项研究成果，发表在《Cell》杂志2015年12月3日这一期上。论文的题目是《High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities》。我们这期节目，就主要围绕这篇文章来进行讲解。
文章的核心内容，就是：
1.用CRISPR方法，把几种肿瘤细胞系的几乎所有的基因都做一遍敲除，也就是“Knock out”。
2.然后用高通量测序，来看哪些基因被敲除之后，细胞的生长会受到抑制。
3.接下来，在几种肿瘤细胞系之间进行比较，看哪个基因，是对一个特定细胞系的生长，是必需的，而在别的细胞系当中，这个基因是非必需的。那么，这个基因就可能是治疗这种肿瘤的，潜在的、新的治疗靶点
本视频详细介绍了这种全新的方法，和用这个方法找到的一系列潜在的新药化合物的实例。
生命科学在智利的新发展
在美国度过25年后,巴伦苏埃拉重新回到智利，他创办生命科学相关的基金会，去表明科学对经济和社会发展的重要性，他相信，投资在科学研究将改善智利目前的经济，并有助于推动它在新的方向前进。
RNAscope原位杂交技术助力新冠病毒检测及初步结果展示
RNAscope原位杂交技术助理新冠病毒检测及初步结果展示 1. RNAscope技术原理介绍 2. 在Zika，MERs-Cov，HIV等病毒研究中的应用实例 3. RNAscope应对新冠病毒研究的相关产品及结果展示
被移植的心脏如何重新跳动的?
TransMedics’ proprietary Organ Care System (OCS) is the first commercial and portable warm blood perfusion organ transport system. With the OCS, doctors are able to perform “living organ transplants,” where organs are kept warm and functioning in a controlled environment from the time they are recovered to the moment they are placed in the recipient’s body.
研究寄生虫的质体，提供药物开发的新靶点
David Roos (U Penn) Part 2: The apicomplexan plastid
Antibiotics are effective because they kill bacteria without harming humans and other eukaryotes (organisms with cells that contain nuclei). So why are the eukaryotic parasites responsible for malaria and toxoplasmosis killed by drugs like clindamycin? Multidisciplinary studies integrating molecular genetics, cell biology, biochemistry, pharmacology and computational genomics reveal that such drugs target an unusual organelle. The "apicoplast" was acquired when an ancestral organism 'ate' a eukaryotic alga, and retained the algal plastid -- a relative of plant chloroplasts derived from a bacterial ancestor. Although no longer photosynthetic, the apicoplast is essential for parasite survival, providing new targets for drug development. See more at http://www.ibioseminars.org