朱宝利：肠道微生物多年研究的总结和体会-第3段
人体肠道微生态与肠道黏膜免疫性疾病的关系——与肠道菌群的关系
肠道细菌特意菌群和人体特定疾病关联性的研究——高血压、心血管疾病、心理性
药物代谢与肠道微生物组
观察活体细胞的有丝分裂过程
Early microscopic images of cells and subcellular organelles were obtained using fixed cells. In this lecture, Dr. Inoue recalls how, in 1947, he built a polarizing light microscope that allowed him to visualize, for the first time, the dynamic mitotic spindle in live cells.
细胞质处理小体(P-小体)和mRNA的周期
Roy Parker (U. Colorado Boulder/HHMI) Part 2: P-bodies and the mRNA Cycle
In the second part of this lecture, I will provide an overview of why the regulation of translation and mRNA degradation is an important aspect of the control of gene expression in eukaryotic cells. In addition to the translating pool of mRNAs associated with polysomes, recent experiments have identified P-bodies and stress granules as specific cytoplasmic compartments wherein untranslated mRNAs accumulate. In addition to mRNAs, P-bodies tend to contain translation repressors and mRNA degradative enzymes, while stress granules reflect mRNAs in association with some translation initiation factors and RNA binding proteins. P-bodies and stress granules interact and suggest a dynamic process wherein eukaryotic mRNAs remodel their interacting proteins and enter and exit translation, thereby affecting the control of mRNAs in the cytoplasm. We are interested in defining the mechanisms by which P-bodies and stress granules assemble and how cells regulate the movement of mRNAs between these different biochemical and cell biological compartments. Several approaches will be described including biochemical and genetic analyses of known proteins modulating these events, as well as the identification of new factors affecting P-body and stress granule formation and function.
In 2012, Roy Parker joined the University of Colorado, Boulder after many years at the University of Arizona.
研究寄生虫的质体，提供药物开发的新靶点
David Roos (U Penn) Part 2: The apicomplexan plastid
Antibiotics are effective because they kill bacteria without harming humans and other eukaryotes (organisms with cells that contain nuclei). So why are the eukaryotic parasites responsible for malaria and toxoplasmosis killed by drugs like clindamycin? Multidisciplinary studies integrating molecular genetics, cell biology, biochemistry, pharmacology and computational genomics reveal that such drugs target an unusual organelle. The "apicoplast" was acquired when an ancestral organism 'ate' a eukaryotic alga, and retained the algal plastid -- a relative of plant chloroplasts derived from a bacterial ancestor. Although no longer photosynthetic, the apicoplast is essential for parasite survival, providing new targets for drug development. See more at http://www.ibioseminars.org
GE：微载体在贴壁细胞大规模培养中的应用
内容主要讲述了微载体的本质属性以及关键参数，以及这些参数在细胞放大培养过程中的关键作用。微载体球转球放大过程中的注意事项。
GE：常温稳定的核酸储存与检测体系
核酸样品越来越多冰箱不够用？核酸样品与检测试剂冷链运输费用昂贵？常温稳定的核酸储存与检测体系也许可以帮助您解决类似问题。核酸的常温采集，运输和储存方案可以帮您节约成本，简化流程。而采用稳定化保存的检测试剂，可无需冷链运输即可保持试剂活性，节约运输成本。
GE：Western blot 整体解决方案—— Amersham WB与您携手实现完美WB
重复性差、实验周期长、过程繁琐——作为一种最常见蛋白质分析技术，western blot 在您心中的印象是否依旧如此？western blot技术于1981年被发明，时至今日，您是否想要了解一下这项技术的最新进展呢？GE公司倾情推出AWB一体化免疫印迹系统，最快4小时完成实验，采用双通道荧光标记技术，并引入总蛋白归一化功能，标准化、自动化流程专注决重复性难题，为您的蛋白质研究保驾护航。
GE：抗体药物开发中细胞培养基的筛选、优化与补料策略
在抗体药物的开发过程中如何选择合适的无血清细胞培养基，在实验结果未达到预期要求时，如何做培养基的优化，及feed-batch培养模式下，如何优化补料策略，来提升细胞状态、延长表达周期、提高抗体产量。
GE：在单抗药物的上游整体解决方案
通过本次讲座您将能够了解GE在单抗药物的上游整体解决方案。 讲座内容将涉及如何使用WAVE波浪型生物反应器通过灌注培养获得高密度细胞达到1×108c/ml，完成种子细胞制备将Split ratio提高到1:50-1:100；如何使用一次性生物反应器XDR200实现CHO细胞高密度培养达到30 x 106c/ml，并结合中空纤维技术实现高密度灌注培养；同时还将涉及一次性配液系统如何实现pH、电导、温度的自主反馈调节，并进行数据记录，以更满足GMP法规要求等。
2016第二弹之细胞治疗中病毒载体的下游纯化
近年来，以CAR-T为代表的的特异性细胞免疫治疗为攻克癌症带来了一丝曙光，越来越多的创业公司及科研单位纷纷投身于该领域，方兴未艾！在细胞治疗整个流程中涉及细胞分选，培养，质粒及病毒包装纯化等，高品质的病毒载体在CAR-T疗法中至关重要。病毒载体的纯化方式可分为：超滤法，超高速离心法以及层析法等。其中，层析法对设备要求低，具有时间短，通量高，纯度高和易于放大的特点，是一种非常重要的病毒载体纯化手段。在本次报告中，我们将讨论如何利用不同的层析介质以及合理的衔接步骤对病毒载体进行纯化。