在染色体分离中有关长度和数量的问题 - Richard McIntosh P1
本视频由科普中国和生物医学大讲堂出品
Richard McIntosh (U. Colorado, Boulder) Part 1: Separating Duplicated Chromosomes
The goal of these three talks is to define the problems that a cell faces as it prepares for division and to describe some of the ways it solves them. In Part 1, both the length and amount of DNA are presented as problems for chromosome segregation, particularly in eukaryotic cells. The actions of cohesins and of chromosome condensation are described as solutions. The mitotic machinery is introduced, including its diversity of form across phylogeny, however, the features that appear to be conserved are emphasized. This lecture may be useful for upper level undergraduate and graduate courses discussing mitosis and cell division. See more at www.ibioseminars.org
有丝分裂后期:染色体向纺锤体两极移动 - Richard McIntosh P3
本视频由科普中国和生物医学大讲堂出品
Richard McIntosh (U. Colorado, Boulder) Part 3: Moving Chromosome to the Spindle Poles: Anaphase A
The third lecture presents evidence, largely from McIntosh's lab, that shows how microtubule depolymerization can move chromosomes in vitro and explores the nature of some of the protein complexes that can couple chromosomes to microtubules and take advantage of this reaction. See more at http://www.ibioseminars.org
细胞遗传学单元(染色体核型技术与细胞收集器)
Karyotype analysis is a laboratory technique where the chromosomes from one cell are visualized under a microscope to investigate the total number and structure of the chromosomes
荧光原位杂交和染色体核型分析
A video protocol and description of Fluorescence In Situ Hybridization (FISH) in plants. The following two companion resources contain recipes, probe plasmid data, and other information needed for doing the procedures illustrated in this video. Of further interest are suggestions for developing a karyotyping cocktail for other plant species and making probes from BAC DNA.
刘玉:花生四烯酸脂代谢在染色体17p缺失肿瘤中的作用
介绍了染色体17p缺失,17p缺失小鼠模型,提到了造血干细胞的分化,p53以外的其他17p13基因对肿瘤的驱动作用等。