曹德骏：从Bioplex应对临床需求和质控角度探讨新诊断技术如何满足临床实际需求
主要内容包括:新技术的开创和革新，历程和关注，成功产品的要素，临床诊断的需求，液相芯片技术历史，高速灵敏的新技术，检测流程的革新，对传统技术的全面革新，数字PCR技术的浪潮，ddPCR技术前景广阔
Margaret：细胞研究和治疗的监管标准
Margaret教授就细胞研究和治疗的监管标准将何去何从发表了演讲。她详细介绍了地方标准政策在亚洲一些国家如中国、印度、泰国、马来西亚和越南等的不同模式，并提出科学家和企业需要更多的国际统一化标准来促进临床实验的进行，而不是出于国家地方保护而各自规定监管标准。
Study the pathological features of diseases using induced pluripotent stem cells derived form patient's somatic cells
The limited experimental access to disease-affected human tissues has severely impeded the elucidating of molecular mechanisms underlying disease development. Generation of induced pluripotent stem cells (iPSCs) by over-expression of defined transcription factors in somatic cells, in particular in those from patient somatic cells, presents an attractive and promising approach to model the early stages of diseases in vitro and to screen novel biomarkers as well as therapeutic medicines. Recently, many research groups have independently reported that patient-specific iPSC-derived cells recapitulated multiple features of pathological events of a particular disease, offering experimental evidence of utilizing patient-specific iPSCs to model diseases and reevaluate the current therapies. We have derived iPSC lines using somatic cells of patients suffering from Klinefelter's Syndrome (KS) and Alzheimer's Disease (AD) and explored the possibility to use these iPSC lines to recapitulate the pathological features of the diseases. Our results show that patient's specific iPSC lines provide good opportunity to study the development and treatment of diseases.
Regenerative medicine for brain and nerve repair
We isolated and propagated neural stem cells from the exposed brain tissue of the patients with open brain trauma, and then implanted neural stem cells with MRI-guided stereotactic device for the patients. Within 2-years follow-ups, the patients were investigated for functional recovery. Contrast to the case control group, implantation of neural stem cells was associated with a significant improvement in patient's neurological function. Investigations of stem cell therapy have required analysis of the fate and migration of implanted neural stem cells. Here, We demonstrate the feasibility of labeling human neural stem cells and retinal stem cells with nanoparticle and tracking of implanted cells in monkey and human central nervous system (CNS). This data demonstrates the possibility of stem cell therapy in CNS and collectively provide necessary foundation for overcoming challenges to the enhancement of translational regenerative medicine of brain and optic nerve injury.
New Trends in RNA-Seq
来自Illumina China的测序产品经理余菽亮，分别从以下几个方面做了详细介绍： 在RNA序列的新的趋势，RNA序列的好处，RNA序列的挑战RNA序列的进化，TruSeq Standed RNA dUTP method ，提供完整的rRNA转录覆盖更多还原，TruSeq @ RNA库准备概述，单细胞测序的方法个别肿瘤细胞的转录组分析，细胞类型特异性基因表达标记，Fluidigm单细胞自准备系统概述等。
Novel signaling by the IKK complex
Signal transduction plays a pivot role in regulating cell functions, from proliferation, differentiation, programmed cell death, and transformation. Deregulation of signal transduction could lead to various human diseases even cancer. Extracellular signals are transmitted into cells via an intracellular signaling network that is composed of multiple signaling pathways, dictating cellular functions, such as growth, differentiation, programmed death (apoptosis) and transformation.
Although we have learnt a great deal about the architecture of the intracellular signaling network, our understanding of its biology is limited. The work in my laboratory focuses on elucidating molecular mechanisms underlying plasticity and specificity of intracellular signaling network using c- Jun N-terminal protein kinase (JNK) and IkB kinase (IKK)/NF-kappaB as molecular probes and understanding the impact of deregulating the intracellular signaling network on human diseases
Yuji Heike：免疫治疗（治疗癌症的sellular位置）
国际癌症中心（NationalCancerCenter）的YujiHeike教授则带来了癌症的细胞免疫治疗方法。他认为今后组合疗法是癌症治疗的主流方法，并对癌症免疫疗法进行了详细介绍。以PD-1在肺癌中的免疫疗法为案例进行了详细阐述。最后他还号召全亚洲能够加入ACTO，共同合作研究。
JSR Life Sciences诊断试剂原料
诊断试剂原料类产品包括：诊断试剂用原料（乳胶微球、磁性粒子、封闭剂）、研究用材料试剂（超常磁珠、粒子和功能配体）、和标准离子。主要用于诊断试剂的研发与生产、蛋白质与核酸的分离、微粒子计数器的校正等。
JSR Life Sciences业务介绍
捷时雅（上海）商贸有限公司是JSR 集团在中国的全资子公司，其生物技术部全面负责JSR Life Sciences公司及其控股子公司的生物工艺器材、诊断试剂原料和医用高分子材料等产品在中国的市场推广、销售和技术支持工作。生物工艺器材类产品包括：亲和层析填料（protein A 亲和填料）、离子交换层析膜（NatriFlo HD-Q)、三维细胞培养耗材及试剂（SCIVAX)等，主要用于新药候选物筛选、药物毒性评估、生物医药工业的下游分离和纯化及大规模制备生产等领域；
small RNA-seq - 陈巍学基因（9）
本期课程介绍：
1、small RNA建库测序的方法；
2、small RNA测序数据的生物信息学分析（A、表达量差异分析；B、聚类分析；C、GO分析；D、KEGG Pathway分析）；
3、血清和血浆micro RNA测序的意义、和样本准备