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2015-01-26 课时:32分钟

Interplays between Mesenchymal Stem Cells and Immune Responses

Mesenchymal stem cells (MSCs) exist in almost all tissues and are crucial in maintaining the cellular homeostasis of multicellular organisms. They provide the ultimate cell source for tissue repair and regeneration. Under pathological conditions, these cells are awakened, activated, and mobilized to damaged tissue sites. Since tissue damages are often accompanied by inflammatory factors, from both innate immune response and adaptive immune response, it is sensible that MSCs delicately interact with inflammatory factors at the sites of tissue damages.

Depending on the type and persistence of the inflammatory factors, the activated MSCs could lead either to complete or partial tissue repair, or to chronic inflammation and further tissue damage, such as cancer and fibrosis. Indeed, recent studies have shown that there is a bidirectional interaction between MSCs and inflammatory cells and cytokines. However, much information of this information remains to be elucidated. Further investigations in this newly emerging exciting research area will undoubtedly lead to better understanding of pathogenesis of various diseases and novel treatment strategies.

2015-01-29 课时:27分钟

SynVivo的应用

SynVivo是一款模拟体内血管环境的微流体芯片,可以模拟仓鼠、大鼠和小鼠的不同血管。提供形态和生物学仿真微环境,可以对药物等微粒与细胞的相互作用进行实时观察研究,其中一些特殊芯片可以培养特定组织类型的细胞,如神经元、肝细胞或肿瘤细胞等。 SynVivo在体外条件下,利用微循环网络模拟在体条件下细胞/微粒粘附、细胞-细胞或细胞-微粒相互作用。研究流体和形态对药物研发和细胞研究的影响.。得到剪切力-粘附效应图,分叉与分支粘附效应等。研究人员只需用适当的底物覆盖微芯片的通道(如纤连蛋白),然后在其中培养细胞,就可以建立人工的体内环境。这一系统可通过流动的液体来模拟天然的血液。
SynVivo在细胞行为、药物粒子粘附和吸收机制、药物输送、药物发现、药物毒性分析等领域有广泛应用。

2015-01-30 课时:4分钟

Discovery: Innovations with Ed Begley Jr

美国著名的《Discovery》频道创新系列节目《Innovations with Ed Begley Jr》全球播出了艾森生物最新研发的新一代实时心肌功能评价系统(xCELLigence RTCA CardioECR)。

本期节目主要关注在医疗健康领域的突破性进展。节目用七分多钟时间报道了艾森生物实时心肌细胞检测这项突破性的技术发明,并通过目前用药安全方面的问题调研及业内知名专家的采访,阐明了该发明在药物早期心脏毒性评价、用药安全、高通量新药筛选、心脏基础研究方面的价值和意义。

2015-02-03 课时:7分钟

Cell and chemical biology of mitosis

2015-03-02 课时:33分钟

Cell and chemical biology of mitosis

2015-03-02 课时:41分钟

Cell and chemical biology of mitosis

2015-03-02 课时:41分钟

Cell and chemical biology of mitosis

2015-03-02 课时:23分钟

Targets-based therapy for leukemia: opportunity and challenge

优点主要为:能增强患者的免疫力,防止肿瘤的转移和复发,对病人机体的损伤小。 在我国,现在普遍开展的树突状细胞(DC)和细胞因子诱导的杀伤细胞(CIK)的生物疗法被广泛应用。

2015-03-03 课时:41分钟

Genomics in the “Century of Biology

完整基因组测序已为包括肺癌在内的若干种癌症类型的突变谱提供了线索。最新测序技术意味着,现在有可能从全基因组范围内来观察突变差异,而且现在研究人员对肺癌已经做到了这一点

2015-03-03 课时:41分钟