如何随处种小型森林
人栽种森林之後,任其自然生长,通常至少需要经过一百年才能长大成熟。但是如果我们能让这个过程快十倍会如何呢?在这场简短的演说中,生态企业家苏沙马解释如何随处打造迷你森林生态系统。
我们是如何挖掘出棘龙的
棘龙生活于9700万年前,长达50英尺,善于在水中捕获猎物,是“久远时代的大恐龙”。考古学家 Nizar Ibrahim 和他的同事们在撒哈拉沙漠的悬崖里挖掘出了新的化石,帮助我们认识了迄今为止(人类发掘的)第一种能够在水里游泳的恐龙——可能也是世界上最大的肉食性恐龙。
脑对脑沟通已来临 - 我们是如何做到的
你或许记得神经学家Miguel Nicolelis — 他建造的脑控骨骼机器人能够让一个瘫痪患者在2014年世界杯开球。他现在在做些什么呢?设计出让两个两种不同的大脑(目前为止是老鼠和猴子)相互发送信息。视频的最后一个实验,如他所说,将会“挑战想象力的极限。”
年轻的血液如何能逆转年龄?真的可以
托尼•魏斯-科瑞研究衰老对人类身体和大脑有怎样的影响。在这场令人大开眼界的演讲中,他展示了他的斯坦福实验室以及其他团队的最新研究成果,也许治疗某些衰老问题的灵药就在我们的身体里。
如何绿化沙漠并扭转气候变化
“荒漠化是个华丽的词,用来描述正在变成沙漠的土地,”艾伦·萨弗瑞(Allan Savory)用这句话开始了这个强有力的演讲。可怕的是,世界上三分之二的草地正在变成沙漠,加快了气候变化并导致传统放牧社会陷入混乱。萨弗瑞奉献一生的时间来制止它。现在他相信——他的工作也显示了——一个惊人的因素能保护草原并恢复退化成沙漠的土地。
如何解冻被冷冻保存的外周血单核细胞或细胞系。
Thawing of cryopreserved PBMC's or cell lines. Thawing procedure for peripheral blood mononuclear cells (PBMC's) or cell lines cryopreserved in liquid nitrogen (LN2).
非包膜病毒如何侵入细胞 - Stephen Harrison P3
本视频由科普中国和生物医学大讲堂出品
Stephen Harrison (Harvard) Part 3: Non-enveloped virus entry
Harrison begins his talk by asking why most non-enveloped viruses and some enveloped viruses are symmetrical in shape. He proceeds to show us lovely images of the structures obtained by x-ray crystallography of numerous viral coat proteins. Deciphering these structures allowed scientists to understand that viral coat proteins form multimers, such as dimers and pentamers, which in turn interact with a scaffold that ensures that the coat proteins are correctly placed. This arrangement results in symmetrically shaped viruses.
In Part 1, Harrison also explains that enveloped viruses infect cells by inducing the fusion of the viral and host cell membranes. He delves deeper into the molecular mechanism of membrane fusion driven by the hemagglutinin or HA protein of the influenza virus in Part 2 of his talk.
Non-enveloped viruses, on the other hand, must enter cells by a mechanism other than membrane fusion. This is the focus of Part 3. Using rotavirus as a model, Harrison and his colleagues have used a combination of Xray crystallography and electron cryomicroscopy to decipher how the spike protein on the viral surface changes its conformation and perforates the cell membrane allowing the virus to enter the cell.
牛痘病毒如何进入细胞 - Ari Helenius P3
本视频由科普中国和生物医学大讲堂出品
Ari Helenius (ETH Zurich) Part 3: Open Sesame: Cell Entry and Vaccinia Virus
Part 3 focuses on a single virus, the Vaccinia virus, as a model for cell binding, signaling and endocytosis. Fluorescently labeled Vaccinia viruses bind to and surf along host cell filopodia. Helenius lab members noticed that when Vaccinia, unlike other viruses, reached the surface of the cell body it caused the plasma membrane to form blebs. Further experiments showed that the virus tricks the cell into thinking it is apoptotic debris. This induces blebbing and subsequent uptake of the virus by macropinocytosis. Additionally, automated high throughput siRNA screening was used to screen a large number of infected cells for host genes required for Vaccinia virus uptake. Analysis of the genes identified allowed host factors and processes critical to viral infection to be identified. Expansion of this technique may provide a new source of information on pathogen-host interactions.
小熊直播第1期:如何赚取MedSci积分
欢迎收看小熊直播课堂节目,今天小熊教大家,如何在“MedSci医学”APP上来赚取积分!
除了购买积分外,总共有以下4种免费获取积分的方式哦~
一.注册即送10个积分
下载打开"MedSci医学"APP,在【我】里面,点击【立即登陆】,在登录页面选择【注册】,完成注册,即可获得10个积分。
官方下载地址:http://www.medsci.cn/m/
二.每日签到领取积分
每天,打开"MedSci医学"APP,在【我】里面,点击【签到+1积分】,即可获得1个积分。
三.资讯评论获得积分
打开"MedSci医学"APP,进入我们的【资讯】页面,评论相关资讯,即可获得2个积分。
四.分享好友送积分
打开"MedSci医学"APP,在【我】里面,点击【邀请好礼】,把里面的【邀请码】分享给好友。好友下载打开APP,输入你的验证码,你即可获得20个积分。
我是如何成为一名科学家的 - Alfredo Quinones-Hinojosa
本视频由科普中国和生物医学大讲堂出品
Alfredo Quinones-Hinojosa(Q博士)(霍普金斯达大学):我是如何成为一名科学家
出生于墨西哥的Q博士,19岁时翻越美国边界的栅栏,成为加利福尼亚的一名农场工人。由于他自己的决心,努力工作和自律,以及来自家庭和朋友的大量支持,他离开了农场工作,完成了大学和医学院的学业,最终成为一位非常成功的医生、科学家和脑外科医生。
关于讲师:Alfredo Quinones-Hinojosa是约翰霍普金斯大学,神经外科学和肿瘤学,神经系统的细胞与分子医学的副教授,脑肿瘤外科手术的主任。Q博士作为一个专家外科医生,他致力于干细胞,在脑肿瘤的病因和治疗领域的研究。
Alfredo Quinones-Hinojosa (Dr. Q) (Johns Hopkins): How I Became a Scientist
At age 19, Quiñones-Hinojosa jumped the fence from Mexico to become a farm worker in California. Thanks to his own determination, hard work and discipline and a lot of support from family and friends, he left farm work, completed university and medical school, and ultimately became a highly successful physician-scientist and brain surgeon.
About the speaker: Alfredo Quiñones-Hinojosa is an Associate Professor of Neurosurgery and Oncology, Neuroscience and Cellular and Molecular Medicine and Director of the Brain Tumor Surgery Program at Johns Hopkins University. As well as being an expert surgeon, he researches the role of stem cells both in causing brain tumors and potentially in fighting them.
This talk was first released in iBioMagazine Issue 5.
下载生物谷APP,观看行云学院视频,让播放更流畅,使用更快捷!
生物谷APP,每天都有新资讯,每天都有好视频!
官方下载地址:http://www.medsci.cn/m/