EZH2通过诱导异染色质形成来沉默 microRNA-218的表达
陈扬超博士就胰腺癌高风险基因EZH2通过诱导异染色质形成来沉默microRNA-218的表达的报告内容。
在染色体分离中有关长度和数量的问题 - Richard McIntosh P1
本视频由科普中国和生物医学大讲堂出品
Richard McIntosh (U. Colorado, Boulder) Part 1: Separating Duplicated Chromosomes
The goal of these three talks is to define the problems that a cell faces as it prepares for division and to describe some of the ways it solves them. In Part 1, both the length and amount of DNA are presented as problems for chromosome segregation, particularly in eukaryotic cells. The actions of cohesins and of chromosome condensation are described as solutions. The mitotic machinery is introduced, including its diversity of form across phylogeny, however, the features that appear to be conserved are emphasized. This lecture may be useful for upper level undergraduate and graduate courses discussing mitosis and cell division. See more at www.ibioseminars.org
有丝分裂后期：染色体向纺锤体两极移动 - Richard McIntosh P3
本视频由科普中国和生物医学大讲堂出品
Richard McIntosh (U. Colorado, Boulder) Part 3: Moving Chromosome to the Spindle Poles: Anaphase A
The third lecture presents evidence, largely from McIntosh's lab, that shows how microtubule depolymerization can move chromosomes in vitro and explores the nature of some of the protein complexes that can couple chromosomes to microtubules and take advantage of this reaction. See more at http://www.ibioseminars.org
神经组织的组织学染色
为了检测组织和器官中的细胞，结构和分子的布局，研究人员使用一种被称为组织学染色的方法。在该技术中，感兴趣的组织被用化学固定剂保存并切片，或切成非常薄的切片。然后应用各种染色技术为这些看起来均一的切片提供对比度。在神经解剖学的研究中，组织学技术被经常用来观察和研究神经系统组织。
这段视频着重于神经组织的组织学染色技术。概述了常见的大脑组织染色，包括那些特异性标记神经元细胞体的方法，如尼氏染色，和那些有选择地突出显示髓鞘化的轴突的方法，如罗克沙尔固蓝染色。还讨论了免疫组化技术，该技术利用抗体和特定细胞蛋白之间的特异性相互作用。接下来，描述了制备用于染色的脑组织样品，包括固定，包埋，切片和复水组织的基本步骤。本短片还提供了免疫组织染色后进行尼氏染色的逐步过程，以及这些技术的实际应用。
细胞遗传学单元（染色体核型技术与细胞收集器）
Karyotype analysis is a laboratory technique where the chromosomes from one cell are visualized under a microscope to investigate the total number and structure of the chromosomes
荧光原位杂交和染色体核型分析
A video protocol and description of Fluorescence In Situ Hybridization (FISH) in plants. The following two companion resources contain recipes, probe plasmid data, and other information needed for doing the procedures illustrated in this video. Of further interest are suggestions for developing a karyotyping cocktail for other plant species and making probes from BAC DNA.
支原体检测：赫斯特DNA染色
This AbVideo tells you how to detect Mycoplasma in vero cell samples through the “Hoechst DNA staining method”, since one of the most important cell culture procedures is to use microtest to identify whether mycoplasmal contaminant is present or not. More videos at Abnova http://www.abnova.com
刘玉：花生四烯酸脂代谢在染色体17p缺失肿瘤中的作用
介绍了染色体17p缺失，17p缺失小鼠模型，提到了造血干细胞的分化，p53以外的其他17p13基因对肿瘤的驱动作用等。