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霍乱弧菌群体感应和新型抗生素 - Bonnie Bassler P2

本视频由科普中国和生物医学大讲堂出品

Bonnie Bassler (Princeton) Part 2: Vibrio Cholerae Quorum Sensing and Novel Antibiotics

Bacteria, primitive single-celled organisms, communicate with chemical languages that allow them to synchronize their behavior and thereby act as enormous multi-cellular organisms. This process is called quorum sensing and it enables bacteria to successfully infect and cause disease in plants, animals, and humans. Investigations of the molecular mechanisms underlying quorum sensing are leading to the development of novel strategies to interfere with quorum sensing. These strategies form the basis of new therapies to be used as antibiotics. See more at http://www.ibioseminars.org

2015-12-14 课时:20分钟

朱运峰:外周血游离DNA作为新型肿瘤标志物在肿瘤筛查以及疗效评估中的作用

介绍了1、外周血游离DNA相关概念及研究背景。2、临床价值.3、肿瘤发生与基因突变。4、神奇的胞嘧啶及其脱氢酶。

2017-08-31 课时:40分钟

杨青:新型IDO抑制剂的发现及其治疗人类重大疾病的作用

介绍了Tryptophan metabolism ,IDO(indoleanmine 2,3-dioxygenase)。IDO and Alzheimer’ disease (AD).IDO mediated immunotolerance,IDO-tumor immunoescape、immune checkpoint、drug design target等

2017-12-04 课时:0分钟

杨青:新型IDO抑制剂的发现及其治疗人类重大疾病的作用

介绍了Tryptophan metabolism ,IDO(indoleanmine 2,3-dioxygenase)。IDO and Alzheimer’ disease (AD).IDO mediated immunotolerance,IDO-tumor immunoescape、immune checkpoint、drug design target等

2017-12-15 课时:26分钟

新型肿瘤免疫疗法的机制研究与开发策略

肿瘤免疫治疗,是一种通过激活人体自身免疫系统对抗肿瘤的治疗手段。近年来,随着免疫疗法的迅猛发展,肿瘤免疫治疗已广泛应用于多种恶性肿瘤的治疗。肿瘤免疫治疗在复发.. ...

2021-07-22 课时:30分钟