在染色体分离中有关长度和数量的问题 - Richard McIntosh P1
本视频由科普中国和生物医学大讲堂出品
Richard McIntosh (U. Colorado, Boulder) Part 1: Separating Duplicated Chromosomes
The goal of these three talks is to define the problems that a cell faces as it prepares for division and to describe some of the ways it solves them. In Part 1, both the length and amount of DNA are presented as problems for chromosome segregation, particularly in eukaryotic cells. The actions of cohesins and of chromosome condensation are described as solutions. The mitotic machinery is introduced, including its diversity of form across phylogeny, however, the features that appear to be conserved are emphasized. This lecture may be useful for upper level undergraduate and graduate courses discussing mitosis and cell division. See more at www.ibioseminars.org
扩大模型系统的数量是了解人类的本质生物学与疾病
受资助和资源影响的科学家，都集中在一个小数量的模型生物的研究。的á桑切斯Alvarado认为，理解生物的多样化可以为我们提供了深入了解以前未知的生物过程。通过排泄途径，的á桑切斯Alvarado显示广泛的拓扑和之间的遗传相似性脊椎动物的肾脏和涡虫原肾管。事实上，基因突变导致人类多囊性肾脏病涡虫具有相似的病理学。这些研究结果反映了非传统模式生物的能力提供深入了解生物学和人类疾病。