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胚胎发育的模式

Following fertilization, the single celled embryo undergoes a number of mitotic divisions to produce a ball of cells called a blastula or blastoderm. Although these cells are all genetically identical, they gradually begin to express different gene products that reflect the regions of the adult body they will form. In my first lecture I discuss how these initial patterns of gene expression arise. In Drosophila, a maternally supplied transcription factor called Bicoid plays a particularly important role. Bcd RNA is anchored at the anterior end of the egg but is only translated after fertilization. From that anterior source, Bcd protein is thought to diffuse through the egg, establishing a concentration gradient that activates different genes at different thresholds. See more at http://www.ibioseminars.org

2016-04-21 课时:29分钟

徐晨:microRNAs与精子发生和胚胎发育

介绍了microRNAs相关作用及研究背景,microRNAs模式,microRNAs在睾丸精子发生和胚胎发育中的表达变化等。以及一些在老鼠模型中的研究案例。

2017-07-27 课时:34分钟

薛志刚:环境因素与早期胚胎发育研究

介绍了项目背景及立项依据,建立的早期胚胎干细胞测序平台及加权基因共表达网络分析方法(WGCNA)。提到了胚胎外环境—PH值,氧气对胚胎的影响。人类生殖技术的一些问题。介绍了自己课题组的一些工作。

2017-07-27 课时:30分钟