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生物糖组成像方法 - Carolyn Bertozzi P2

本视频由科普中国和生物医学大讲堂出品

Carolyn Bertozzi (UC Berkeley) Part 2: Imaging the Glycome

Since glycans cannot be labeled with genetically-encoded reporters such as GFP, bioorthoganal reactions have been developed to allow their labeling and imaging. In this lecture, Bertozzi describes the chemistry and imaging methodology used to view glycoproteins in cells and whole organisms. See more at http://www.ibioseminars.org

2015-12-14 课时:58分钟

头足纲动物的伪装和信号 - roger Hanlon P1

本视频由科普中国和生物医学大讲堂出品

roger Hanlon (MBL) Part 1: Camouflage and Signaling in Cephalopods

Hanlon introduces the amazing adaptive coloration of cephalopods. He uses video and still photography to showcase their ability to rapidly change color, pattern and skin texture with fine control and a diversity of appearances, to produce camouflage or to send signals. He argues that all camouflage patterns in nature can be grouped into three types. In part 2, Hanlon shows us results from his lab that make a convincing case that the rapid adaptive coloration of cephalopods is controlled by their visual system; quite impressive for a color-blind animal! Part 3 focuses on the unique skin of cephalopods including the system of pigments and reflectors that allows it to quickly change to any hue and contrast, and the papillae musculature that allows the skin to deform and create multiple 3D textures.

2015-12-14 课时:29分钟

对头足纲动物视觉感知机制的探索 - roger Hanlon P2

本视频由科普中国和生物医学大讲堂出品

roger Hanlon (MBL) Part 2: Exploring Mechanisms of Visual Perception

Hanlon introduces the amazing adaptive coloration of cephalopods. He uses video and still photography to showcase their ability to rapidly change color, pattern and skin texture with fine control and a diversity of appearances, to produce camouflage or to send signals. He argues that all camouflage patterns in nature can be grouped into three types. In part 2, Hanlon shows us results from his lab that make a convincing case that the rapid adaptive coloration of cephalopods is controlled by their visual system; quite impressive for a color-blind animal! Part 3 focuses on the unique skin of cephalopods including the system of pigments and reflectors that allows it to quickly change to any hue and contrast, and the papillae musculature that allows the skin to deform and create multiple 3D textures.

2015-12-14 课时:52分钟

头足纲动物的可变化的皮肤细胞 - roger Hanlon P3

本视频由科普中国和生物医学大讲堂出品

roger Hanlon (MBL) Part 3: Changeable Skin

Hanlon introduces the amazing adaptive coloration of cephalopods. He uses video and still photography to showcase their ability to rapidly change color, pattern and skin texture with fine control and a diversity of appearances, to produce camouflage or to send signals. He argues that all camouflage patterns in nature can be grouped into three types. In part 2, Hanlon shows us results from his lab that make a convincing case that the rapid adaptive coloration of cephalopods is controlled by their visual system; quite impressive for a color-blind animal! Part 3 focuses on the unique skin of cephalopods including the system of pigments and reflectors that allows it to quickly change to any hue and contrast, and the papillae musculature that allows the skin to deform and create multiple 3D textures.

2015-12-14 课时:32分钟

Controlling the Cell Cycle: Introduction - David O. Morgan

本视频由科普中国和生物医学大讲堂出品

David O. Morgan (UCSF) Part 1: Controlling the Cell Cycle: Introduction

Cells reproduce by duplicating their chromosomes and other components and then distributing them into a pair of genetically identical daughter cells. This series of events is called the cell cycle. In the first part of this lecture, I provide a general overview of the cell-cycle control system, a complex regulatory network that guides the cell through the steps of cell division. I briefly describe the major components of this regulatory system and how they fit together to form a series of biochemical switches that trigger cell-cycle events at the correct time and in the correct order.

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2016-01-07 课时:29分钟

Controlling the Cell Cycle: Cdk Substrates - David O. Morgan

本视频由科普中国和生物医学大讲堂出品

David O. Morgan (UCSF) Part 2: Controlling the Cell Cycle: Cdk Substrates

Cyclin-dependent kinases (Cdks) are the central components of the control system that initiates the events of the cell cycle. In the second part of this lecture, I discuss my laboratory's efforts to address the problem of how the Cdks trigger cell-cycle events. I describe our methods for identifying the protein substrates of the Cdks, and I discuss how these studies have led to important clues about how Cdks find their correct targets in the cell and how phosphorylation of those targets governs their function.

2016-01-08 课时:31分钟

Controlling the Cell Cycle: Anaphase Onset - David O. Morgan

本视频由科普中国和生物医学大讲堂出品

David O. Morgan (UCSF) Part 3: Controlling the Cell Cycle: Anaphase Onset

In the anaphase stage of the cell cycle, the duplicated chromosomes are pulled apart by a machine called the mitotic spindle, resulting in the distribution of a complete set of chromosomes to each of the daughter cells. In the third part of this lecture, I describe the combination of biochemistry and microscopy in my laboratory that led to the discovery of a regulatory switch that triggers the abrupt and synchronous separation of the chromosomes at the onset of anaphase.

2016-01-08 课时:22分钟

Photoreceptors and Image Processing Part 1A - Jeremy Nathans

本视频由科普中国和生物医学大讲堂出品

Jeremy Nathans (Johns Hopkins) Part 1A: Photoreceptors and Image Processing

In this set of lectures, Jeremy Nathans explores the molecular mechanisms within the retina that mediate the first steps in vision. The first lecture focuses on the structure of the light sensing receptors, the intracellular signals that are triggered by light absorption, and the ways in which the retina extracts information from a complex scene. See more at http://www.ibioseminars.org

2016-01-08 课时:36分钟

Photoreceptors and Image Processing Part 1B - Jeremy Nathans

本视频由科普中国和生物医学大讲堂出品

Jeremy Nathans (Johns Hopkins) Part 1B: Photoreceptors and Image Processing

In this set of lectures, Jeremy Nathans explores the molecular mechanisms within the retina that mediate the first steps in vision. The first lecture focuses on the structure of the light sensing receptors, the intracellular signals that are triggered by light absorption, and the ways in which the retina extracts information from a complex scene. See more at http://www.ibioseminars.org

2016-01-08 课时:34分钟

布鲁斯·艾伯茨:Learning from Failure

Alberts declares "Success doesn't really teach you much, failure teaches you a lot." Speaking from his personal experience, Alberts asserts that all scientists make mistakes and suffer setbacks but learning from those failures is what allows one ultimately to succeed.

2016-01-26 课时:12分钟