打开APP

Diabetes Care:高剂量的咖啡摄入或可有效降低2型糖尿病风险

  1. 2型糖尿病
  2. Diabetes Care
  3. 咖啡
  4. 风险
  5. 高剂量

来源:生物谷 2014-02-19 00:03

发表在国际杂志Diabetes Care上的一篇研究论文中,来自哈佛大学公共卫生学院的研究人员通过研究表明,咖啡的高剂量摄取和低风险的2型糖尿病直接相关。

2014年2月19日 讯 /生物谷BIOON/ --近日,发表在国际杂志Diabetes Care上的一篇研究论文中,来自哈佛大学公共卫生学院的研究人员通过研究表明,咖啡的高剂量摄取和低风险的2型糖尿病直接相关。

文章中,研究者Ming Ding和其研究团队对28个前瞻性研究和巢式病例对照研究进行了系统性综合分析,力求评估个体咖啡的摄入和其患2型糖尿病风险之间的关系。

研究者发现,相比不摄入咖啡或者低水平摄入的个体来讲,个体每天喝一杯咖啡患2型糖尿病的相对风险为0.92(95%的置信区间),每天喝2杯咖啡患2型糖尿病的风险为0.85,每天喝3杯咖啡患2型糖尿病的风险为0.79,而每天喝4杯的则为0.75,每天喝5杯患糖尿病的风险为0.71,每天喝6杯咖啡的个体患2型糖尿病风险为0.67。

研究者表示,每天饮用含咖啡因的咖啡和不含咖啡因的咖啡相比,二者对糖尿病风险的降低并无明显差异。研究者在文中写道,咖啡的大剂量摄入和2型糖尿病风险降低直接相关,而且含咖啡因或者不含咖啡因的咖啡均和糖尿病风险降低相关。(生物谷Bioon.com)

doi:10.2337/dc13-1203
Diabetes Care

Caffeinated and Decaffeinated Coffee Consumption and Risk of Type 2 Diabetes: A Systematic Review and a Dose-Response Meta-analysis

Ming Ding1, Shilpa N. Bhupathiraju1, Mu Chen1, Rob M. van Dam1,2 and Frank B. Hu1,3,4⇑

OBJECTIVE

Previous meta-analyses identified an inverse association of coffee consumption with the risk of type 2 diabetes. However, an updated meta-analysis is needed because new studies comparing the trends of association for caffeinated and decaffeinated coffee have since been published.

RESEARCH DESIGN AND METHODS

PubMed and Embase were searched for cohort or nested case-control studies that assessed the relationship of coffee consumption and risk of type 2 diabetes from 1966 to February 2013. A restricted cubic spline random-effects model was used.

RESULTS

Twenty-eight prospective studies were included in the analysis, with 1,109,272 study participants and 45,335 cases of type 2 diabetes. The follow-up duration ranged from 10 months to 20 years. Compared with no or rare coffee consumption, the relative risk (RR; 95% CI) for diabetes was 0.92 (0.90–0.94), 0.85 (0.82–0.88), 0.79 (0.75–0.83), 0.75 (0.71–0.80), 0.71 (0.65–0.76), and 0.67 (0.61–0.74) for 1–6 cups/day, respectively. The RR of diabetes for a 1 cup/day increase was 0.91 (0.89–0.94) for caffeinated coffee consumption and 0.94 (0.91–0.98) for decaffeinated coffee consumption (P for difference = 0.17).

CONCLUSIONS

Coffee consumption was inversely associated with the risk of type 2 diabetes in a dose-response manner. Both caffeinated and decaffeinated coffee was associated with reduced diabetes risk.

版权声明 本网站所有注明“来源:生物谷”或“来源:bioon”的文字、图片和音视频资料,版权均属于生物谷网站所有。非经授权,任何媒体、网站或个人不得转载,否则将追究法律责任。取得书面授权转载时,须注明“来源:生物谷”。其它来源的文章系转载文章,本网所有转载文章系出于传递更多信息之目的,转载内容不代表本站立场。不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。

87%用户都在用生物谷APP 随时阅读、评论、分享交流 请扫描二维码下载->