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JCEM:维生素D有益改善肺结核患者肺功能

  1. 维生素D
  2. 肺功能
  3. 肺结核

来源:生物谷 2013-03-26 21:39

2013年3月22日 讯 /生物谷BIOON/ --保持足够的维生素D水平可以帮助人们呼吸更顺畅,甚至可能防止结核病(TB),根据最近一项发表在Journal of Clinical Endocrinology & Metabolism杂志上的研究证实。 涉及有1万多名韩国成年人参与的这项研究发现,当人们自己身体吸收更多的维生素D后,肺功能得到明显改善。

2013年3月22日 讯 /生物谷BIOON/ --保持足够的维生素D水平可以帮助人们呼吸更顺畅,甚至可能防止结核病(TB),根据最近一项发表在Journal of Clinical Endocrinology & Metabolism杂志上的研究证实。

涉及有1万多名韩国成年人参与的这项研究发现,当人们自己身体吸收更多的维生素D后,肺功能得到明显改善。维生素D主要是通过太阳光吸收,健康的饮食习惯作为辅助来源。

如果没有足够的维生素D来帮助钙的吸收,儿童和成人可会出现骨骼和肌肉疾病。科学家了解了维生素D如何改善肺功能以及骨骼健康。这项研究确定了心肺功能和血液中的维生素D水平之间有明确联系。

这一联系不分年龄,性别,体重或生活方式。这项研究发现有TB的人体内维生素D的生物标志物25-羟基维生素D水平显著降低,在这一人群中25-羟基维生素D水平上升时,肺功能得到改善。

研究人员推测维生素D可以提高患者的先天免疫力,帮助他们从感染中恢复过来,并调控肺组织退化。这项研究表明TB患者可能受益于维生素D治疗,以改善他们的肺功能。

维生素D也可能是潜在的结核病预防性措施,但需要更多的研究以探讨维生素D对肺结核的影响。(生物谷:Bioon.com)

Relationship between Serum 25-Hydroxyvitamin D and Lung Function among Korean Adults in Korea National Health and Nutrition Examination Survey (KNHANES), 2008- 2010

Chan-Jin Choi,et al.

Maintaining adequate levels of vitamin D can help people breathe better and may even protect against tuberculosis (TB), according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).The study of more than 10,000 Korean adults found that lung function improved when people had absorbed more vitamin D into their bodies. Vitamin D is absorbed primarily through sunlight, with a healthy diet as a secondary source.Without enough vitamin D to aid calcium absorption, children and adults can develop bone and muscle conditions. The study improved scientists' understanding of how vitamin D may improve lung function as well as bone health."The research identified a clear connection between lung function and vitamin D levels in the blood," said the study's lead author, Chan-Jin Choi, MD, PhD, of the Catholic University of Korea's College of Medicine. "The link remained in place, regardless of age, gender, weight or lifestyle."The study found people who had a history of TB had significantly lower levels of the vitamin D biomarker, called 25-hydroxyvitamin D (25(OH)D), in their blood. Lung function improved in this population when 25(OH)D levels rose.Researchers theorize vitamin D could enhance patients' innate immunity, help them recover from infection and regulate lung tissue degradation."This study suggests TB patients may benefit from receiving vitamin D therapy to improve their lung function," Choi said. "Vitamin D also has potential as a preventative measure for TB. More research is needed to explore the impact vitamin D has on the condition."People who already are taking the recommended dose of vitamin D supplements may not need to change their routine to reap the benefits the vitamin has on lung function. The study found negligible benefit for people whose vitamin D biomarker levels exceeded the range 16.5-24.9 ng/ml, which is well below the levels The Endocrine Society recommends for bone health in its guidelines.

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