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利用核磁共振快速筛查乳腺癌风险

来源:生物谷 2016-03-08 09:50

2016年3月8日讯/生物谷BIOON/乳房密度高是患乳腺癌的一个独立危险因素。核磁共振(MRT)对乳腺癌的诊断来说是最安全的方法,目前用于早期诊断。维也纳医科大学放射学和临床核医学研究人员已经成功地开发了一种乳腺密度的精确测量的方法,使用核磁共振成像仪(MRT)检测Dixon序列。使用核磁共振成像仪除了可以进行更好的乳腺癌诊断外,也可以进行风险评估。

世界范围内首次用一种全自动软件和较高精度及重现性来客观测量乳房密度的方法目前只存在一种原型。“实际上只需触摸一个按钮,花费几分钟的时间就可以。也不需要提供对比材料” Georg Wengert说。

根据ACR(美国放射学院)称乳腺密度分为四个类别:从A到D, 对于较高乳腺密度的人患乳腺癌的风险被认为高出四到六倍 (C /异构和D /密度极高)。使用乳房x光检查和超声波扫描不能精确测量乳腺密度,另外较高的乳房密度使诊断更加困难。

这就是为什么维也纳医科大学专家建议增加使用MRT进行风险评估,诊断和早期诊断:“我们致力于更好的解释为何女性乳房x光检查和超声无法检测所有癌症。MRT真的是一种推荐的好方法”。 Wengert说,检测有更好的有效性,因此有助于迅速引入正确的治疗措施。

每年大约5400名奥地利人患乳腺癌

乳腺癌是女性中最常见的癌症,将近三分之一的人在她们的生活中要面对此病。据统计约在奥地利2011年约有5400名妇女患乳腺癌,同年,约有1500名妇女死于该病。

(生物谷Bioon.com)

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A high breast density is an independent risk factor for breast cancer. MRT is the safest method for breast cancer diagnosis and is now used for early diagnosis. Medical University Vienna researchers at the University Clinic for Radiology and Nuclear Medicine have now successfully developed a method for the exact measurement of breast density using magnetic resonance tomography (MRT) examinations with the Dixon sequence. With this, in addition to a better breast cancer diagnosis, a better assessment of the risk is also possible.  For the first time worldwide an objective measurement of breast density, with fully automatic software and higher precision and reproducibility, has been detected with this method, and a prototype currently exists. "It works practically at the touch of a button and only takes a few minutes. There is also no need to provide contrast material", says Georg Wengert from the University Clinic for Radiology and Nuclear Medicine at Medical University Vienna, who is presenting the results at the largest European Congress of Radiologists, which is taking place in Vienna from 2 to 6 March 2016. The study was undertaken by the Molecular and Gender Imaging Working Group under the management of Thomas Helbich (University Clinic for Radiology and Nuclear Medicine) and the Computational Imaging Research (CIR) Laboratory developed the software under the management of Georg Langs (University Clinic for Radiology and Nuclear Medicine). Breast density is divided into four categories according to the guidelines of the ACR (American College of Radiology): Ranging from A to D, the risk of getting breast cancer is considered to be four to six times higher for a higher breast density (C/heterogeneous and D/extremely dense). The density cannot be precisely measured using mammography and an ultrasound scan, and additionally a high breast density makes diagnosis more difficult. That is why Medical University Vienna experts recommend increasing the use of MRT for risk assessment, diagnosis and early diagnosis: "We are committed to better explaining to women that the use of mammography and ultrasound alone cannot detect all carcinomas. MRT really is the recommended method", says Wengert. The examination has a far better validity, and therefore helps to quickly introduce the right therapeutic steps. Every year around 5,400 Austrians fall ill with breast cancer Breast cancer is the most common cancer in women, nearly one third will be confronted with this in their lives. According to statistics around 5,400 women became ill from breast cancer in Austria in 2011, and in the same year around 1,500 women died from this cancer. Five research clusters at Medical University Vienna In total, five research clusters have been established at Medical University Vienna. At Medical University Vienna the focus on key areas in fundamentals and clinical research has been increased. The research clusters cover medical imaging, cancer research/oncology, cardiovascular medicine, medical neuroscience and immunology. These results fall under the subject area of the cluster for medical imaging.

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