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惊!吸二手烟大大增加中风患病风险

来源:生物谷 2015-07-14 09:34

                                                     

     
2015年7月13日讯 /生物谷BIOON/ --在美国,每年有大约800,000人受到中风的折磨,每19例死亡就有一例与中风有关,同时中风还是导致行动不便的首要因素。最近一项研究表明,二手烟会导致非吸烟者的中风患病几率增加30%。
 
研究人员利用一项针对45岁以上白种人和非裔美国人的大型调查研究数据发现,即使是在对一些已知的可导致中风发生的因素,比如高血压,糖尿病和心脏疾病进行校正之后,非吸烟者仍有30%的中风风险。
 
目前这项研究包括了大约22,000名志愿者,其中有23%的人报告曾有二手烟暴露情况。从2003年4月到2012年3月,共有428人发生中风。研究人员进一步对中风的类型进行分析发现大部分中风患者是由于大脑血管堵塞而发病。
 
虽然并不是所有的研究都重复了二手烟暴露与中风之间的关系,但二手烟对健康的危害已经越来越明了。
 
研究人员指出,之前一些研究受到研究视角的局限,对一些潜在因素的校正各不相同,除此之外由于衡量方法和数据来源也存在不同,并不是所有的研究都将中风的亚型考虑在内进行评估,还有一些研究受到小样本量的限制,因此二手烟暴露与中风之间的关系没有得到比较一致性的确认。
 
总得来说,这项研究基于大样本量群体研究,在对一些可导致中风发生的因素进行校正之后,发现非吸烟者暴露在二手烟环境下会增加中风风险,这为进一步严格控烟政策提供了流行病学研究依据。  (生物谷Bioon.com)
 
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Secondhand Smoke Exposure and Stroke: The Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study
 
Angela M. Malek, PhD1, , , Mary Cushman, MD2, Daniel T. Lackland, DrPH3, George Howard, DrPH4, Leslie A. McClure, PhD
 
Introduction
 
Stroke is a major public health concern worldwide given the associated morbidity and mortality. Smoking is a risk factor for stroke, but the relationship between secondhand smoke (SHS) exposure and stroke has been inconsistent to date. The aim of the current study was to examine the association of SHS exposure and risk of stroke and its subtypes (ischemic and hemorrhagic stroke) among nonsmokers.
 
Methods
 
Demographic and clinical characteristics were compared by SHS exposure status for African American and white nonsmokers aged ≥45 years in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study in 2014. Hazard ratios (HRs) and corresponding 95% CIs were calculated by Cox proportional hazards models to assess the relationship between SHS exposure and stroke risk.
 
Results
 
Of the 21,743 participants (38% African American, 45% male), SHS exposure in the past year was reported by 23%. Compared with those without SHS exposure, exposed participants were more likely to be female, white, younger, and reside with a smoker (allp<0.001). A total of 428 incident strokes were observed from April 2003 to March 2012 during a mean follow-up of 5.6 years. The risk of overall stroke was increased 30% among those with SHS exposure after adjustment for other stroke risk factors (95% CI=2%, 67%). This relationship appeared to be driven by ischemic strokes.
 
Conclusions
 
SHS exposure is independently associated with an increased risk of stroke. Future studies are needed to confirm these findings and examine the role of long-term effects of SHS exposure on stroke outcomes.
 
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