打开APP

科学家开展了对新型猪流感病毒的监测

  1. H2N3
  2. 基因重排
  3. 猪流感病毒
  4. 监测

来源:生物谷 2015-03-05 09:44

--随着季节性流感病例在美国各地的减少,近日来自堪萨斯州立大学的研究者开始了对新一代流感病毒毒株的监测工作,这项工作是以对猪体内的流感病毒开始研究的,研究人员利用国立卫生研究所提供了资助进行了猪体内流感病毒的大量研究。

2015年3月5日 讯 /生物谷BIOON/ --随着季节性流感病例在美国各地的减少,近日来自堪萨斯州立大学的研究者开始了对新一代流感病毒毒株的监测工作,这项工作是以对猪体内的流感病毒开始研究的,研究人员利用国立卫生研究所提供了资助进行了猪体内流感病毒的大量研究。

研究者Richt讲道,猪流感在不断发生改变,其存在一种持续的突变比率,有时候猪流感病毒会通过基因重排的机制发生着快速的改变,基因重排就是一种流感病毒的基因片段同其它不同的流感病毒的基因片段相混合形成的复杂形式。目前研究人员非常关注为何这些基因可以产生在人类机体中不存在的病毒表面蛋白。

研究者收集了来自堪萨斯州兽医诊断实验室及阿比林动物医院的患病猪的样本,通过对这些样本进行分析研究者就可以确定是否猪流感会对人类带来潜在的威胁;猪流感病毒可以感染猪并且引发猪患呼吸道疾病,但其有时候也会通过猪传染给人类,研究者希望可以较早地发现新型的猪流感病毒以便其可以对病毒进行分离研究其特性,从而提醒政府进行有效控制来尽可能早地消除新型的猪流感病毒。

研究人员进行相关研究已经6年了,此前他们在密苏里州的猪体内发现了一种新型的流感病毒亚型,这种名为H2N3的新型流感病毒是通过鸭流感病毒和当地的猪流感病毒进行基因重排后所形成的一种新型的流感病毒,其对人类健康具有一定的威胁,随着研究者进行有效及时地监测,这种病毒在其扩散前就已经被消灭了。

最后研究者Ma说道,我们认为进行新型流感病毒的监测非常重要,因为流感病毒是公众健康及动物健康的一大威胁,相关研究也为工业和农业生产提供了一定的有效信息和预警。(生物谷Bioon.com)

本文系生物谷原创编译整理,欢迎转载!转载请注明来源并附原文链接。更多资讯请下载生物谷APP.

生物谷推荐的新闻阅读:

The work is starting with swine in the field. Juergen Richt, Regents distinguished professor of veterinary medicine and director of the U.S. Department of Homeland Security's Center of Excellence for Emerging and Zoonotic Animal Diseases, and Wenjun Ma, assistant professor of diagnostic medicine and pathobiology, are surveying for swine influenza viruses as part of a $1 million grant from the National Institutes of Health.

"Swine influenza are constantly changing," Richt said. "There's a constant mutational rate, and sometimes they're changing very rapidly using a mechanism called reassortment -- gene segments from one influenza virus are mixed with gene segments from a different influenza virus. We are very concerned about these genes coming together to create new surface proteins that have not been seen in the human population."

The researchers are collecting samples from diseased pig populations recorded by the Kansas State Veterinary Diagnostic Laboratory and the Abilene Animal Hospital. These samples are analyzed to determine if the swine influenza could be a danger to humans.

"Swine influenza viruses infect swine and cause a respiratory disease in pigs, but they sometimes have the ability to transmit from pigs to humans," Richt said. "We hope that we are early enough in discovering these novel swine influenza viruses so that we can isolate and characterize these viruses and alert the respective authorities to control and eradicate them as soon as possible."

The Kansas State University research team has been working on this project for six years. It previously discovered a novel influenza subtype in swine from Missouri. Richt says this novel H2N3 virus was created through a reassortment from a duck influenza virus and an endemic swine influenza virus, which could have been very dangerous to human health. As the team monitored the influenza, the virus died out before it could spread.

"I think it is very important work because influenza is a threat to public health and animal health. We are providing very important information for the industry and for public health," Ma said.

 

版权声明 本网站所有注明“来源:生物谷”或“来源:bioon”的文字、图片和音视频资料,版权均属于生物谷网站所有。非经授权,任何媒体、网站或个人不得转载,否则将追究法律责任。取得书面授权转载时,须注明“来源:生物谷”。其它来源的文章系转载文章,本网所有转载文章系出于传递更多信息之目的,转载内容不代表本站立场。不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。

87%用户都在用生物谷APP 随时阅读、评论、分享交流 请扫描二维码下载->