新功能、新界面、新体验,扫描即可下载生物谷APP!
首页 » 高血压 » JAND:蓝莓,有效降低高血压及动脉硬化

JAND:蓝莓,有效降低高血压及动脉硬化

来源:生物谷 2015-01-13 11:05

 

2015年1月13日 讯 /生物谷BIOON/ --试想一下,如果在你的早餐麦片中加入一杯蓝莓,那么你就赶快干掉它吧!近日,一项发表于国际杂志Journal of the Academy of Nutrition and Dietetics上的一篇研究论文中,来自佛罗里达州立大学的研究人员通过研究表明,每天一杯蓝莓或可有效降低机体血压和动脉硬化,而这两种疾病都和心血管疾病直接相关。

研究者Sarah A. Johnson表示,有规律地食用蓝莓或可潜在减缓个体从高血压前期向高血压发展的进程,从而可以有效降低心血管疾病的风险;我们非常有兴趣致力于功能性食品对人体的作用机理,对人类机体健康具有促进效应的食品往往可以抑制和逆转机体的不良健康状况,尤其是对于绝境后女性而言。

在美国心血管疾病是引发个体死亡的主要原因,一旦妇女经历更年期,其就会处于较高风险的心血管疾病中,研究发现,单一食物,比如蓝莓的额外补充会有效减缓绝经后女性出现负面的心血管疾病风险。文章中,研究人员对48名绝经后处于前期及第一阶段高血压的个体进行了为期8周的研究,参与个体每日服用22克的冷冻蓝莓粉(相当于一杯新鲜蓝莓),同时另一组每日服用等量的安慰剂粉;在此同时两组参与者均进行正常的饮食及锻炼。

在研究初期,研究者测定了参与者的血压、动脉硬化程度以及选择性的高血压标志物的水平;在8周实验结束后,每日服用蓝莓粉的个体收缩压降低了7mmHg(5.1%),舒张压降低了5 mmHg(6.3%);此外,服用蓝莓粉组的个体的动脉硬化程度降低了97 cmcond (6.5%)。同时研究人员发现,一种血液生物标志物—一氧化氮可以使得血管扩张68.5%,由于动脉硬化和血管变窄是高血压的典型标志,因此一氧化氮水平的提高或可帮助揭示血压为何降低了。

此前对蓝莓的研究揭示了蓝莓对心血管疾病风险因子的正面效应,但是这需要消耗大量的蓝莓粉(50-250g),以250g蓝莓粉为例,其相当于11杯新鲜蓝莓,这这些量对于个体每天服用来讲或许并不现实。

最后研究者Jonhson表示,未来研究中我们或许会考虑利用其它剂量的蓝莓粉来对相同参与对象进行长期的干预研究;相关研究由U.S. Highbush Blueberry Council提供资助。(生物谷Bioon.com)

本文系生物谷原创编译整理,欢迎转载!转载请注明来源并附原文链接。谢谢!

Daily Blueberry Consumption Improves Blood Pressure and Arterial Stiffness in Postmenopausal Women with Pre- and Stage 1-Hypertension: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Sarah A. Johnson, PhD, RD, CSO, Arturo Figueroa, MD, PhD, FACSM, Negin Navaei, Alexei Wong, PhD, Roy Kalfon, MS, Lauren T. Ormsbee, MS, Rafaela G. Feresin, MS, Marcus L. Elam, MS, Shirin Hooshmand, PhD, Mark E. Payton, PhD, Bahram H. Arjmandi, PhD, RD

Background Postmenopausal women have a high prevalence of hypertension and often develop arterial stiffness thereby increasing cardiovascular disease risk. Although antihypertensive drug therapies exist, increasing numbers of people prefer natural therapies. In vivo studies and a limited number of clinical studies have demonstrated the antihypertensive and vascular-protective effects of blueberries. Objective To examine the effects of daily blueberry consumption for 8 weeks on blood pressure and arterial stiffness in postmenopausal women with pre- and stage 1-hypertension. Design This was an 8-week, randomized, double-blind, placebo-controlled clinical trial. Participants/setting Forty-eight postmenopausal women with pre- and stage 1-hypertension recruited from the greater Tallahassee, FL, area participated. Intervention Participants were randomly assigned to receive either 22 g freeze-dried blueberry powder or 22 g control powder. Main outcome measures Resting brachial systolic and diastolic blood pressures were evaluated and arterial stiffness was assessed using carotid-femoral pulse wave velocity and brachial-ankle pulse wave velocity. C-reactive protein, nitric oxide, and superoxide dismutase were measured at baseline, 4 weeks, and 8 weeks. Statistical analyses performed Statistical analysis was performed using a split plot model of repeated measures analysis of variance. Results After 8 weeks, systolic blood pressure and diastolic blood pressure (131±17 mm Hg [P<0.05] and 75±9 mm Hg [P<0.01], respectively) and brachial-ankle pulse wave velocity (1,401±122 cm/second; P<0.01) were significantly lower than baseline levels (138±14 mm Hg, 80±7 mm Hg, and 1,498±179 cm/second, respectively), with significant (P<0.05) group×time interactions in the blueberry powder group, whereas there were no changes in the group receiving the control powder. Nitric oxide levels were greater (15.35±11.16 μmol/L; P<0.01) in the blueberry powder group at 8 weeks compared with baseline values (9.11±7.95 μmol/L), whereas there were no changes in the control group. Conclusions Daily blueberry consumption may reduce blood pressure and arterial stiffness, which may be due, in part, to increased nitric oxide production.

温馨提示:87%用户都在生物谷APP上阅读,扫描立刻下载! 天天精彩!


相关标签

最新会议 培训班 期刊库