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首页 » 临床研究 » Vaccine:新措施有效改善青少年HPV疫苗接种率的

Vaccine:新措施有效改善青少年HPV疫苗接种率的

来源:生物谷 2014-12-30 14:34

2014年12月30日 讯 /生物谷BIOON/ --一般来讲,改变医生的行医方式是很困难的,近日,一项刊登于国际杂志Vaccine上的研究论文中,来自波士顿大学医学中心的研究人员通过研究表示,将质量改进及激励措施同传统的教育相结合或许可以改善男孩儿和女孩儿的人乳头瘤病毒(HPV)疫苗的接种率,该研究或为持续性改善HPV疫苗的接种率提供帮助。

每年大约有300万美国人寻找治疗HPV相关疾病的疗法,2.7万美国人都患有HPV相关的癌症,而5000多人死于相关的疾病;HPV疫苗可以潜在保护个体抵御70%因HPV病毒引发的癌症,但是目前只有不到一半的青少年进行了三种必须疫苗的接种。

这项研究中,研究人员利用一种多组分的性能继续医学教育改善(PI CME)干预措施,其中就包括同医生们进行重复性地接触、重点教育及个体化的反馈等步骤,同时激励医生们完成新的医学专业委员会的认证,这种干预措施在两个联邦合格的医疗中心及六个相同的健康护理网络中心进行,结果研究人员发现,相比对照的健康中心而言,提供干预的中心女孩儿接种疫苗的可能性是前者的2倍,而男孩儿接种疫苗的可能性则为10倍。

近来有研究强调了接种HPV疫苗的重要性,而本文中研究者阐明了提供PI CME干预策略对于改善HPV疫苗接种率的重要性,研究者Rebecca Perkins说道,目前许多美国人遭受着HPV相关癌症的痛苦,而早日接种疫苗则会保护其抵御相关疾病的发生,医生们目前通过对所有的病人进行接种来消除其它疫苗可预防的疾病,而进行HPV疫苗的接种也会帮助有效改善年轻个体的健康状况。

研究者认为,将多组分的持续医学教育同通过电子医学记录获得的常规数据进行结合,或许就可以使得这种干预措施被广泛采纳;他们希望未来可以将这种教育程度更广泛地应用于其它健康系统中来更有效地改善易感个体的HPV的接种率。(生物谷Bioon.com)

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Effectiveness of a provider-focused intervention to improve HPV vaccination rates in boys and girls

Rebecca B. Perkinsa, , , , Lara Zisblattb, Aaron Leglerc, Emma Trucksb, Amresh Hanchated, Sherri Sheinfeld Gorine, f

Background HPV vaccination is universally recommended for boys and girls, yet vaccination rates remain low nationwide. Methods We conducted a provider-focused intervention that included repeated contacts, education, individualized feedback, and strong quality improvement incentives to raise HPV vaccination rates at two federally qualified community health centers. To estimate the effectiveness of the intervention, rates of initiation of vaccination, and completion of the next needed HPV vaccination (dose 1, 2 or 3) among boys and girls ages 11–21 were compared at baseline and two follow-up periods in two intervention health centers (n 4093 patients) and six control health centers (n 9025 patients). We conducted multivariable logistic regression accounting for clustering by practice. Results Girls and boys in intervention practices significantly increased HPV vaccine initiation during the active intervention period relative to control practices (girls OR 1.6, boys OR 11; p < 0.001 for both). Boys at intervention practices were also more likely to continue to initiate vaccination during the post-intervention/maintenance period (OR 8.5; p < 0.01). Girls and boys at intervention practices were more also likely to complete their next needed HPV vaccination (dose 1, 2 or 3) than those at control practices (girls OR 1.4, boys OR 23; p < 0.05 for both). These improvements were sustained for both boys and girls in the post-intervention/maintenance period (girls OR 1.6, boys OR 25; p < 0.05 for both). Conclusions Provider-focused interventions including repeated contacts, education, individualized feedback, and strong quality improvement incentives have the potential to produce sustained improvements in HPV vaccination rates.

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