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孕妇婴儿需警惕!抗菌香皂带来健康风险!

来源:生物谷 2014-08-12 09:34

2014年8月12日 讯 /生物谷BIOON/ --美国FDA不得不越来越关注是否应该控制常见抗菌化合物的使用,因为其引发了环境健康专家的不断关注,近日来自国外的科学家通过研究发现,经常暴露于抗菌化合物中的孕妇或者婴儿,恐怕会在以后的生活中面对更多潜在的健康风险。

研究者Benny Pycke表示,我们经常会看到,孕妇和婴儿会经常使用三氯生和三氯卡班,这两种是肥皂等产品中常用的用于杀灭细菌的化合物;研究者在所有孕妇的尿液样本中均检测到了三氯生的存在,而且在大约一半的脐带血样本中也检测到了三氯生,这就意味着三氯生可以通过脐带运输到胎儿机体中去;与此同时研究人员在所有样本中也检测到了三氯卡班。

研究者表示,这就表明这些杀菌的化合物或许会引发人类和动物机体的发育和生育的问题,而且有些研究也表明,添加剂也会诱发细菌的抗生素耐药性的产生,细菌抗生素耐药性的日益恶化是当前全球人类面对的一大健康问题。

尽管我们在日常生活中可以通过洗漱等方式清洗掉三氯生和三氯卡班,但是暴露于这些杀菌化合物的效应却是持续的;如果可以切断这种暴露,那么三氯生和三氯卡班将会很快被稀释掉,当时当前的事实却是随着人们广泛的使用,其已经成为人们日常生活中的必须接触品了。

市场上2000多种产品中都包括三氯生和三氯卡班,比如牙膏、肥皂、地毯、玩具等;研究者Geer说道,我们研究发现,经常使用对羟基苯甲酸丁酯(一种用于化妆品中的抗微生物剂)的孕妇所生的婴儿往往身长较短,当然对婴儿和孕妇自身的长期效应研究者们并未进行长期研究。

如果通过大量研究证实抗微生物化合物的确会影响孕妇和婴儿的健康,那么FDA和生产这些带有抗菌作用的公司就必须更加关注三氯生的使用了;目前明尼苏达州是第一个明令禁止在日常产品中添加抗菌功能的一个大州,其将会在2017年1月生效;一些公司比如强生、宝洁,同时也发表声明以后将不再其产品中添加这些抗菌化合物成分,作为FDA和卫生保护机构更应该关注这些化合物对个体的健康影响。(生物谷Bioon.com)

新闻原文:

As the Food and Drug Administration (FDA) mulls over whether to rein in the use of common antibacterial compounds that are causing growing concern among environmental health experts, scientists are reporting today that many pregnant women and their fetuses are being exposed to these substances. They will present their work at the 248th National Meeting & Exposition of the American Chemical Society (ACS), the world's largest scientific society.

"We looked at the exposure of pregnant women and their fetuses to triclosan and triclocarban, two of the most commonly used germ-killers in soaps and other everyday products," says Benny Pycke, Ph.D. "We found triclosan in all of the urine samples from the pregnant women that we screened. We also detected it in about half of the umbilical cord blood samples we took, which means it transfers to fetuses. Triclocarban was also in many of the samples."

The problem with this, explains Pycke, a research scientist at Arizona State University (ASU), is that there is a growing body of evidence showing that the compounds can lead to developmental and reproductive problems in animals and potentially in humans. Also, some research suggests that the additives could contribute to antibiotic resistance, a growing public health problem.

Although the human body is efficient at flushing out triclosan and triclocarban, a person's exposure to them can potentially be constant.

"If you cut off the source of exposure, eventually triclosan and triclocarban would quickly be diluted out, but the truth is that we have universal use of these chemicals, and therefore also universal exposure," says Rolf Halden, Ph.D., the lead investigator of the study at ASU.

The compounds are used in more than 2,000 everyday products marketed as antimicrobial, including toothpastes, soaps, detergents, carpets, paints, school supplies and toys, the researchers say.

Showing what effect antimicrobials have on people is a challenge. But Halden and Pycke's colleague Laura Geer, Ph.D., of the State University of New York, found at least one interesting result. Geer says the study yielded a link between women with higher levels of another ubiquitous antimicrobial, butyl paraben, which is commonly used in cosmetics, and shorter newborn lengths. The long-term consequences of this are not clear, but Geer adds that, if this finding is confirmed in larger studies, it could mean that widespread exposure to these compounds could cause a subtle but large-scale shift in birth sizes.

State policymakers, the FDA and industry have taken notice of the mounting evidence against triclosan. Minnesota became the first state to pass a ban on the antimicrobial's use in certain products, and it will take effect in January 2017. Some companies, such as Johnson & Johnson and Procter & Gamble, have announced that they are phasing out the compound from some products. At the federal level, the FDA and Environmental Protection Agency are reviewing the use and effects of the compounds.

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