临床研究

以疾病的诊断、治疗、预后、病因为目标;以病人为对象;以群体研究为主要研究方法;以医疗机构为基地的一类医学研究的总称。通过临床研究获得治疗方法的安全性和有效性。在群体中进行药物测试,以期获得剂量、药物作用、不良反应等相关资料,从而对治疗方法进行安全性有效性评价。

新功能、新界面、新体验,扫描即可下载生物谷APP!
首页 » 临床研究 » JIAS:HIV传播的风险环境

JIAS:HIV传播的风险环境

来源:生物谷 2014-07-11 14:15

2014年7月11日 讯 /生物谷BIOON/ --在俄罗斯警方追捕的药物注射者(吸毒人群)往往是导致HIV传播以及过量死亡率的风险因素,近日,刊登在国际杂志Journal of the International AIDS Society上的一篇研究论文中,来自波士顿大学的研究人员通过研究揭示了警察抓捕对药物注射的HIV阳性人群健康程度的影响。

那些被警察抓捕的个体更易于共用针头,这无疑中就增加了HIV传播的概率,而且这项研究中研究者也发现并没有明确的证据显示警察抓捕可以降低个体药物的使用,研究者Karsten Lunze表示,我们已经知道,标记个体的风险行为对于降低吸毒人群HIV的传播率非常重要,而这些人群也往往是HIV感染的高发人群。

本文的研究显示,药物法规、警察抓捕等力度必须加大,这对于预防HIV的扩散非常关键;通过将警方抓捕策略同吸毒者健康状况联系起来,研究人员表示,必须采取一定的干预措施来改变个体的行为,并且将警方的抓捕行为作为HIV风险环境的一部分。

Jeffrey Samet博士说道,利用一定的疗法来进行治疗来取代抓捕吸毒人群,这对于控制HIV的传播以及吸毒个体的健康至关重要,公众的健康和安全必须同时保证,这样才能帮助公众提高预防吸毒以及HIV传播的意识。

未来还需要进行更为深入的研究来将执法环境纳入到吸毒个体的管理中,本文研究可以帮助科学家们揭示在吸毒者药物注射过程中警察干预如何来有效改善,而不是变得更加恶化,这对于有效改善HIV的风险环境非常必要。(生物谷Bioon.com)

Punitive policing and associated substance use risks among HIV-positive people in Russia who inject drugs

Karsten Lunze, Anita Raj, Debbie M Cheng, Emily K Quinn, Carly Bridden, Elena Blokhina, Alexander Y Walley, Evgeny Krupitsky, Jeffrey H Samet

Introduction: Drug law enforcement is part of the HIV risk environment among people who inject drugs (PWID). Punitive policing practices such as extrajudicial arrests for needle possession and police planting of drugs have been described anecdotally in Russia, but these experiences and their associations with risky drug behaviours have not been quantified. This study aims to quantify the burden of extrajudicial police arrests among a cohort of HIV-positive PWID in Russia and to explore its links to drug-related health outcomes. Methods: In a cross-sectional study of 582 HIV-positive people with lifetime injection drug use (IDU) in St. Petersburg, Russia, we estimated the prevalence of self-reported extrajudicial police arrests. We used multiple logistic regression to evaluate associations between arrests and the following outcomes: overdose, recent IDU and receptive needle sharing. Findings: This cohort’s mean age was 29.8 years, 60.8% were male; 75.3% reported non-fatal drug overdose, 50.3% recent IDU and 47.3% receptive needle sharing. Extrajudicial arrests were reported by more than half (60.5%, 95% confidence interval [CI]: 56.5–64.5) and were associated with higher odds of non-fatal drug overdose (AOR 1.52, 95% CI: 1.02–2.25) but not with recent IDU (AOR 1.17, arrests were associated with receptive needle sharing (AOR 1.84, 95% CI: 1.09–3.09). Conclusions: Extrajudicial police arrests were common among this cohort of Russian HIV-positive PWID and associated with non-fatal overdose and, among those with recent IDU, receptive needle sharing. As a part of the HIV risk environment of PWIDs, these practices might contribute to HIV transmission and overdose mortality. Further research is needed to relate these findings to the operational environment of law enforcement and to better understand how police interventions among PWIDs can improve the HIV risk environment.

温馨提示:87%用户都在生物谷APP上阅读,扫描立刻下载! 天天精彩!



相关标签

最新会议 培训班 期刊库