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J Clin Psychiat:研究证实失眠与高血压之间无联系

  1. 失眠
  2. 高血压

来源:生物谷 2014-06-30 09:15

近日一项最新研究的结论对于失眠成年人来说是一个好消息,St. Michael医院的新研究发现,失眠不会把增加患高血压的风险。

2014年6月30日讯 /生物谷BIOON/--近日一项最新研究的结论对于失眠成年人来说是一个好消息,St. Michael医院的新研究发现,失眠不会增加患高血压的风险。

Nicholas Vozoris博士说:病人和医疗服务提供者越来越多的关注失眠的潜在的后果,特别是对心血管系统。如果两者之间有关联,这将会对卫生保健系统至少有两个重大的影响:首先,因为失眠是一种常见的问题,经常是长期持续,很大一部分人就都需要长期筛查高血压的可能性。

其次,医生可能更经常以努力从降血压的角度开安眠药治疗失眠。Vozoris博士说:安眠药已经太频繁使用,与一些严重的副作用包括成瘾,车祸有关。

Vozoris博士说,以往表明失眠和高血压之间联系的研究往往基于少数人。他检查了来自近13,000名参加国家健康和营养调查、一系列旨在评估在美国成人和儿童的健康和营养状况的研究数据。这项调查是独一无二的,它结合了对参与者的面谈和体检。

询问他们的失眠症状,并且分析他们的失眠症状与是否有高血压,服用抗高血压药物或曾测得血压高相关联。调整包括参加者是否接受血压药或安眠药后等因素后,研究发现失眠和高血压之间一般没有关联。

研究结果发表在Journal of Clinical Psychiatry杂志上。(生物谷Bioon.com)

Insomnia Symptom Frequency and Hypertension Risk: A Population-Based Study

Nicholas T. Vozoris, MHSc, MD

Objective: To determine whether increasing frequency of insomnia symptoms is associated with increasing hypertension risk.
Method: This was a large population-based multiyear cross-sectional study. Participants of the 2005–2008 National Health and Nutrition Examination Surveys responding to sleep quality questions were included (n = 12,643). Self-reported insomnia symptoms (ie, difficulty falling asleep, prolonged nocturnal awakening, or undesired early morning awakening, based on DSM-IV-TR, National Institutes of Health, and American Academy of Sleep Medicine criteria) over the past month with and without self-reported short sleep time (ie, < 6 hours) were categorized as 0, 1–4, 5–15, and 16–30 times in the past month. Outcomes included doctor-diagnosed self-reported hypertension made at any point in the past, self-reported current receipt of antihypertensive medications, and measured systolic and diastolic hypertension.

Results: While significant and increasing unadjusted odds of doctor-diagnosed hypertension and current antihypertensive medication receipt were found among individuals with increasing insomnia symptom frequency, these odds ratios (ORs) were for the most part rendered nonsignificant after controlling for covariates (eg, adjusted ORs and 95% confidence intervals [CIs] of current antihypertensive receipt for insomnia symptoms coupled with short sleep time: 1–4 times in the past month: 1.17, 0.78–1.76; 5–15 times in the past month: 1.60, 1.01–2.53; and 16–30 times in the past month: 1.41, 0.93–2.14). Even before controlling for covariates, there were generally no significant positive associations between objectively measured systolic and diastolic hypertension and insomnia symptoms regardless of symptom frequency (eg, unadjusted ORs and 95% CIs of measured systolic hypertension for insomnia symptoms coupled with short sleep time: 1–4 times in the past month: 0.88, 0.53–1.47; 5–15 times in the past month: 1.16, 0.77–1.77; and 16–30 times in the past month: 1.30, 0.95–1.78).

Conclusions: Insomnia symptoms, regardless of their frequency, are generally not significantly positively associated with hypertension. These results have important implications relating to screening and management of patients with insomnia symptoms.

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