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Cancer:体力活动或可有效改善乳腺癌患者的生存期及生存质量

来源:生物谷 2014-06-10 15:14

2014年6月10日 讯 /生物谷BIOON/ --近日,刊登在国际杂志Cancer上的一项研究论文中,来自北卡罗来纳大学的研究者通过研究揭示,个体乳腺癌诊断后的体力活动或许可延长患者的生存期并且改善患者的生存质量;而促进乳腺癌患者的体力活动对患者的益处显而易见,研究者建议乳腺癌患者应多加强自身的体力活动。

美国卫生健康服务部和美国癌症协会建议,为了维持一般的机体健康及预防慢性病,成年人每周至少需要进行150分钟中等强度的体力活动或75分钟的剧烈体力活动;文章中,为了揭示体力活动给乳腺癌患者带来的益处,研究人员Brionna Hair领导其研究团队检测了乳腺癌患者在确诊之后所进行的体力活动的水平和改变情况,研究者对在2008年至2011年年间,44个国家中年龄在20至74岁的1735名诊断出乳腺浸润性癌的个体进行了相关评估研究。

研究结果发现,仅有35%的乳腺癌幸存者满足当前治疗的体力活动指南中关于体力活动的要求,诊断后6个月患者进行体力活动的频率明显下降,平均每一位患者都会减少15个代谢当量小时,大约相当于每周5个小时的健步走;相比白人女性而言,非洲裔美国女性中40%的个体都不能达到当前国际上的体力运动指南要求,尽管其诊断后的体力活动频率和白人女性并无明显差异。研究者表示,在美国意识到非洲裔美国女性会因乳腺癌而发生的高死亡率对于改善患者的生存非常重要。

医疗保健对于改善乳腺癌患者的体力活动,乃至改善个体的生存期非常关键,而当前开发出增加乳腺癌患者体力活动的策略需要进行一定的思考和评估,其对于有效改善患者的预后以及生存质量非常重要。(生物谷Bioon.com)

Racial differences in physical activity among breast cancer survivors: Implications for breast cancer care

Brionna Y. Hair MPH1,*, Sandi Hayes PhD2, Chiu-Kit Tse MSPH1, Mary Beth Bell MPH3 andAndrew F. Olshan PhD1

BACKGROUND Physical activity after breast cancer diagnosis is associated with improved survival. The current study examined levels of and changes in physical activity after breast cancer diagnosis, overall and by race. METHODS Phase 3 of the Carolina Breast Cancer Study assessed both pre- and postdiagnosis physical activity levels in a cohort of 1735 women aged 20 years to 74 years who were diagnosed with invasive breast cancer between 2008 and 2011 in 44 counties of North Carolina. Logistic regression and analysis of variance were used to examine whether demographic, behavioral, and clinical characteristics were associated with activity levels. RESULTS Only 35% of study participants met current physical activity guidelines after diagnosis with breast cancer. A decrease in activity after diagnosis was reported by 59% of patients, with the average study participant reducing their activity by 15 metabolic equivalent task (MET) hours (95% confidence interval [95% CI], 12 MET hours-19 MET hours). After adjustment for potential confounders, when compared with white women, African American women were less likely to meet national physical activity guidelines after diagnosis (odds ratio, 1.38; 95% CI, 1.01-1.88) and reported less weekly postdiagnosis physical activity (12 MET hours vs 14 MET hours; P = .13). In adjusted stratified analyses, receipt of treatment was found to be significantly associated with postdiagnosis activity in African American women (P < 0.01). CONCLUSIONS Despite compelling evidence demonstrating the benefits of physical activity after a diagnosis of breast cancer, it is clear that more work needs to be done to promote physical activity in patients with breast cancer, especially among African American women. Cancer 2014. © 2014 American Cancer Society.

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