打开APP

PNAS:儿童时期贫穷或对成年期的情绪控制有影响

  1. 情绪控制
  2. 贫穷

来源:EurekAlert 2013-10-22 11:30

一项研究发现,儿童时期贫穷可能对控制情绪的大脑区域产生持久的影响。 杏仁核在前额叶皮层(PFC)的控制下探测威胁并对其做出反应;这些大脑区域都在大脑的对压力的情绪响应方面起到了关键作用。杏仁核与前额叶皮层(PFC)的异常活动可能导致了抑郁、焦虑、冲动性攻击行为以及对药物的滥用。Pilyoung Kim及其同事进行了一项纵向fMRI研究从而检查了儿童期家庭收入对成年大脑活动的影响。

一项研究发现,儿童时期贫穷可能对控制情绪的大脑区域产生持久的影响。

杏仁核在前额叶皮层(PFC)的控制下探测威胁并对其做出反应;这些大脑区域都在大脑的对压力的情绪响应方面起到了关键作用。杏仁核与前额叶皮层(PFC)的异常活动可能导致了抑郁、焦虑、冲动性攻击行为以及对药物的滥用。Pilyoung

Kim及其同事进行了一项纵向fMRI研究从而检查了儿童期家庭收入对成年大脑活动的影响。这组作者研究了54名青年成年人,其中半数具有低收入背景,另外一半的参与者在他们9岁时其家庭收入高于贫穷线的2到4倍。当向受试者展示负面图像并要求他们减少他们的情绪反应的强度的时候,这组作者观察到了童年生活贫穷的成年人比其他受试者具有更高的杏仁核活动和减少了的前额叶皮层活动,即便当这组作者控制了成年收入因素之后也是如此。

此外,这组作者发现在9岁时对儿童时期贫穷做出反应的神经学变化受到了9到17岁接触长期的自然和社会压力的进一步驱动。这组作者说,这些发现可能有助于为致力于减少健康水平不一致的干预手段提供信息。(生物谷Bioon.com)

生物谷推荐的英文摘要

Proceedings of the National Academy of the Sciences of the United States of America        doi: 10.1073/pnas.1308240110

Effects of childhood poverty and chronic stress on emotion regulatory brain function in adulthood

Pilyoung Kima,1, Gary W. Evansb, Michael Angstadtc, S. Shaun Hoc, Chandra S. Sripadac, James E. Swainc,d, Israel Liberzonc, and K. Luan Phane,f

Childhood poverty has pervasive negative physical and psychological health sequelae in adulthood. Exposure to chronic stressors may be one underlying mechanism for childhood poverty health relations by influencing emotion regulatory systems. Animal work and human cross-sectional studies both suggest that chronic stressor exposure is associated with amygdala and prefrontal cortex regions important for emotion regulation. In this longitudinal functional magnetic resonance imaging study of 49 participants, we examined associations between childhood poverty at age 9 and adult neural circuitry activation during emotion regulation at age 24. To test developmental timing, concurrent, adult income was included as a covariate. Adults with lower family income at age 9 exhibited reduced ventrolateral and dorsolateral prefrontal cortex activity and failure to suppress amygdala activation during effortful regulation of negative emotion at age 24. In contrast to childhood income, concurrent adult income was not associated with neural activity during emotion regulation. Furthermore, chronic stressor exposure across childhood (at age 9, 13, and 17) mediated the relations between family income at age 9 and ventrolateral and dorsolateral prefrontal cortex activity at age 24. The findings demonstrate the significance of childhood chronic stress exposures in predicting neural outcomes during emotion regulation in adults who grew up in poverty.

版权声明 本网站所有注明“来源:生物谷”或“来源:bioon”的文字、图片和音视频资料,版权均属于生物谷网站所有。非经授权,任何媒体、网站或个人不得转载,否则将追究法律责任。取得书面授权转载时,须注明“来源:生物谷”。其它来源的文章系转载文章,本网所有转载文章系出于传递更多信息之目的,转载内容不代表本站立场。不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。

87%用户都在用生物谷APP 随时阅读、评论、分享交流 请扫描二维码下载->