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罗氏与MPP达成Valcyte供货协议

  1. MPP
  2. Valcyte
  3. 罗氏
  4. 药品专利池组织

来源:生物谷 2013-08-05 22:34

2013年8月5日讯 /生物谷BIOON/ --罗氏(Roche)今日与药品专利池组织(Medicines Patent Pool,MPP)签署了一项协议,增加药物缬更昔洛韦Valcyte,通用名:valganciclovir)的获取。所达成的供应协议,将极大地促进138个发展中国家和新兴国家对Valcyte的获取,供货价将比正常售价低90%。

2013年8月5日讯 /生物谷BIOON/ --罗氏(Roche)今日与药品专利池组织(Medicines Patent Pool,MPP)签署了一项协议,增加药物缬更昔洛韦Valcyte,通用名:valganciclovir)的获取。所达成的供应协议,将极大地促进138个发展中国家和新兴国家对Valcyte的获取,供货价将比正常售价低90%。Valcyte是治疗巨细胞病毒(CMV)的一种关键药物。CMV是一种感染性病毒,可能导致HIV患者视力丧失和更大的死亡风险。(生物谷Bioon.com)

英文原文:Roche adds HIV blindness drug to patent pool, cutting price

Roche and the Medicines Patent Pool Sign Agreement to Increase Access to Medicines to Treat CMV infection in HIV-patients, a major cause of Blindness

The Medicines Patent Pool and healthcare company Roche today announce an agreement to increase access to Valcyte (valganciclovir), a key medicine to treat cytomegalovirus (CMV). CMV is a viral infection that can result in loss of vision and greater risk of death in people living with HIV. This infection affects around 1 in 10 people living with HIV in low-and middle-income countries.

The supply agreement between the Medicines Patent Pool and Roche will substantially improve access to an easy-to-take oral medicine to treat CMV, Valcyte – by making it up to 90% cheaper in 138 developing and emerging countries than it is currently available. The Medicines Patent Pool and Roche will consider adding more countries to the initial scope if there is a need and will also explore licensing and technology transfer as a second step to help local production of Valcyte and increase access to Valcyte in developing countries.

“The agreement announced today will make an oral treatment for CMV available at lower prices, to help break a cycle of lack of screening and treatment in many countries. With medicines available, HIV treatment providers can work on wider diagnosis and treatment and prevent avoidable blindness in people living with HIV,” said Greg Perry, Executive Director of the Medicines Patent Pool.

“This agreement demonstrates how working together can improve the availability of treatments for people in resource-limited countries. Roche is committed to making Valcyte available to patients suffering from HIV-related CMV infections in developing countries. Our aim is to provide access to affordable Valcyte that is produced under quality conditions and increase the number of people who access and benefit from our products,” said Daniel O’Day, COO of Roche Pharma.

Treatment of CMV is typically difficult to administer, requiring several injections to the eye. This requires hospitalisation of patients and care by highly trained staff , which are often not sufficiently available in developing countries. The oral treatment Valcyte is an alternative, but due to a number of reasons, including lack of screening and high prices, patients in developing countries have not been able to receive it.

This lower price should also help create a new market for Valcyte, stimulating greater treatment of CMV. With Roche now supplying lower-cost Valcyte, governments, treatment providers and funders can ramp up efforts to ensure screening for CMV becomes part of routine HIV care and people can access treatments to preserve their sight and extend their lives.

CMV infection is a preventable disease caused by cytomegalovirus (CMV) that attacks the retina of the eye in patients with suppressed immune systems, such as those infected with advanced-stage HIV. CMV is no longer a problem in industrialized countries, but still affects 10.1% (8.7% to 11.4%) of people living with HIV in low- and middle-income countries mainly in Asia, and to a lesser extent in Latin America and Africa1.

Roche has also agreed to license another medicine for use in HIV-related medicines to the Medicines Patent Pool, saquinavir, in case the need arises.

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