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J. Arg. food Chem.:喝葡萄酒或吃葡萄可防晒伤

来源:生命时报 2011-08-30 09:02

去海边度假,除了防晒霜,喝点葡萄酒也能保护皮肤免受日晒之苦。据英国《每日邮报》8月7日报道,《农业与食品化学期刊》(Journal of agricultural and food chemistry )新近发表的一项研究指出,喝葡萄酒或者吃葡萄可以预防晒伤。

紫外线是皮肤的最大杀手,会引起皮肤老化、晒伤,甚至皮肤癌。巴塞罗那大学和西班牙国家研究委员会的研究人员观察了皮肤在太阳紫外线照射下的化学反应——紫外线照射皮肤会激活活性氧,导致DNA氧化,进而激活破坏皮肤细胞的酶。而存在于葡萄中的黄酮类物质可以阻止该化学反应的发生,使皮肤细胞得以存活并免受伤害。指导该研究项目的巴塞罗纳大学生物化学家玛尔塔卡斯坎特说:“葡萄可以防止晒伤,甚至能预防皮肤癌。”

此前研究显示,葡萄酒有助于抑制老年痴呆和前列腺癌等,而其保护皮肤的功效则是最新发现。另外,该研究还可启发科学家,探索将植物中提取的多酚化合物用于护肤防晒。因此专家建议,夏天不妨多吃一些葡萄,或者喝两杯葡萄酒,就能收到不错的防晒效果。(生物谷 Bioon.com)

Protective Effect of Structurally Diverse Grape Procyanidin Fractions against UV-Induced Cell Damage and Death

Cecilia Matito,Neus Agell,Susana Sanchez-Tena,Josep L. Torres,Marta Cascante,

UV radiation leads to the generation of reactive oxygen species (ROS). These molecules exert a variety of harmful effects by altering key cellular functions and may result in cell death. Several studies have demonstrated that human skin can be protected against UV radiation by using plant-derived antioxidants. Here we evaluated the in vitro capacity of several antioxidant polyphenolic fractions from grape, which differ in their degree of polymerization and percentage of galloylation, to protect HaCaT human keratinocytes against UV-induced oxidative damage. These fractions inhibited both basal and UVB- or UVA-induced intracellular ROS generation in this cell line. Consequently, the same fractions inhibited p38 and JNK1/2 activation induced by UVB or UVA radiation. The highest protective effect was for fractions rich in procyanidin oligomers and gallate esters. These encouraging in vitro results support further research and should be taken into consideration into the clinical pharmacology of plant-derived polyphenolic extracts as novel agents for skin photoprotection.

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